North Metropolitan Area Health Service, Perth, Australia.
Soc Psychiatry Psychiatr Epidemiol. 2013 Apr;48(4):621-30. doi: 10.1007/s00127-012-0579-5. Epub 2012 Sep 9.
To identify the external validators of patient clusters according to need in a long-stay inpatient population with schizophrenia.
We recruited without exclusion 112 in-patients with chronic schizophrenia in a long-stay rehabilitation facility of a major psychiatric hospital in Perth, Western Australia. Case managers completed a number of measures for participants, including The Camberwell Assessment of Need-Short Appraisal Schedule, which evaluates health and social needs. Latent class analysis according to patient need was performed to identify clusters within the cohort. One way analysis of variance was used to identify the external validators of these clusters, using variables obtained from the additional study measures (Social Behaviour Schedule, Global Assessment of Function, Basic Everyday Living Skills, Behaviour Rating Inventory of Executive Function-Adult version).
Three distinct needs-based clusters with different external profiles were identified. A "low unmet needs" group (n = 50) with relatively intact executive function, with the least problematic behaviour and most independent functioning; a "high unmet need (drug abstinent)" group (n = 43) with greatest executive dysfunction, most problematic behaviour and least independent function; a "high unmet need (drug using)" group (n = 19), with less severe executive dysfunction, and intermediate relative to the other groups on measures of social behaviour and independent functioning.
The clinical heterogeneity we have identified, which may well be explained by executive dysfunction, suggests further exploration of appropriate assessment and streams of care for those in the rehabilitation setting is warranted.
根据需要,在西澳大利亚珀斯一家主要精神病院的长期住院康复机构中,确定慢性精神分裂症住院患者群体的患者聚类的外部验证器。
我们在西澳大利亚珀斯的一家主要精神病院的长期住院康复机构中,无排除地招募了 112 名慢性精神分裂症住院患者。个案经理为参与者完成了多项评估,包括《坎伯韦尔需求评估-短期评估表》,用于评估健康和社会需求。根据患者需求进行潜在类别分析,以确定队列中的聚类。使用来自额外研究措施(社会行为量表、总体功能评估、基本日常生活技能、执行功能行为评定量表-成人版)获得的变量,采用方差分析来识别这些聚类的外部验证器。
确定了具有不同外部特征的三个不同的基于需求的聚类。一个“低未满足需求”组(n = 50),具有相对完整的执行功能,行为问题最少,独立性最强;一个“高未满足需求(药物戒断)”组(n = 43),具有最大的执行功能障碍,最多的行为问题,最缺乏独立性;一个“高未满足需求(药物使用)”组(n = 19),执行功能障碍较轻,在社会行为和独立功能的测量中,与其他组相比处于中间水平。
我们发现的临床异质性很可能可以用执行功能障碍来解释,这表明需要进一步探索适当的评估和康复环境中的护理途径。