Kohler Sibylle, Tschopp Oliver, Bernays René Ludwig, Schmid Christoph
Endocrinology Department, University Hospital Zurich, Zurich, Switzerland.
BMJ Case Rep. 2012 Sep 7;2012:bcr0220125833. doi: 10.1136/bcr.02.2012.5833.
The authors present the case of a 30-year-old female patient with acromegaly whose disease had not been cured after transcranial neurosurgery, two transsphenoidal surgeries and stereotactic radiosurgery. She required treatment with octreotide and pegvisomant to normalise growth hormone levels. Seven years after the diagnosis of acromegaly, she noticed acute vision loss in her left eye and presented with meningism. She had an intrasellar abscess which was confirmed and treated by surgical drainage. As a result of the abscess, she was cured of acromegaly and able to discontinue both octreotide and pegvisomant.
作者报告了一例30岁的肢端肥大症女性患者的病例,该患者在接受经颅神经外科手术、两次经蝶窦手术和立体定向放射治疗后,疾病仍未治愈。她需要使用奥曲肽和培维索孟进行治疗,以使生长激素水平恢复正常。在肢端肥大症诊断7年后,她注意到左眼急性视力丧失,并出现脑膜刺激征。她患有鞍内脓肿,经手术引流得以确诊和治疗。由于脓肿,她的肢端肥大症得以治愈,并且能够停用奥曲肽和培维索孟。