Alam Md Jahoor, Bhayana Latika, Devi Gurumayum Reenaroy, Singh Heisnam Dinachandra, Singh R K Brojen, Sharma B Indrajit
J Chem Biol. 2012 Jan;5(1):27-34. doi: 10.1007/s12154-011-0066-6. Epub 2011 Sep 9.
We examine the synchrony in the dynamics of localized Ca(2 + ) oscillations among a group of cells exhibiting such complex Ca(2 + ) oscillations, connected in the form of long chain, via diffusing coupling where cytosolic Ca(2 + ) and inositol 1,4,5-triphosphate are coupling molecules. Based on our numerical results, we could able to identify three regimes, namely desynchronized, transition and synchronized regimes in the (T - k(e)) (time period-coupling constant) and (A - k(e)) (amplitude-coupling constant) spaces which are supported by phase plots (Δϕ verses time) and recurrence plots, respectively. We further show the increase of synchronization among the cells as the number of coupling molecules increases in the (T - k(e)) and (A - k(e)) spaces.
我们研究了一组呈现如此复杂钙离子振荡的细胞之间局部Ca(2 +)振荡动力学中的同步性，这些细胞以长链形式连接，通过扩散耦合，其中胞质钙离子和肌醇1,4,5 -三磷酸是耦合分子。基于我们的数值结果，我们能够在(T - k(e))（时间周期 - 耦合常数）和(A - k(e))（振幅 - 耦合常数）空间中识别出三种状态，即去同步、过渡和同步状态，分别由相位图（Δϕ与时间的关系）和递归图支持。我们进一步表明，在(T - k(e))和(A - k(e))空间中，随着耦合分子数量的增加，细胞间的同步性增强。
