Department of Clinical Sciences/Ophtalmology, Umeå University, Umeå, Sweden.
Acta Ophthalmol. 2013 Nov;91(7):657-9. doi: 10.1111/j.1755-3768.2012.02491.x. Epub 2012 Sep 11.
To compare the mydriatic effect of intracameral mydriatics injected into the anterior or the posterior chamber in routine phacoemulsification cataract surgery.
Forty-four patients planned for unilateral phacoemulsification surgery were included after informed consent. Mydriasis was achieved by injecting 150 μl of a mixture of phenylephrine 1.5% and lidocaine 1.0% at the beginning of the procedure. The patients were randomly assigned to injection into the anterior or the posterior chamber. The pupils were filmed during the procedures, and the mean pupil diameters were measured at predetermined intervals from the video recordings by an independent observer.
Immediately after the injection, the pupils were larger after posterior chamber injection (3.8 ± 0.8 versus 3.1 ± 0.7 mm; p = 0.004). A similar difference was seen after the phacoemulsification (6.4 ± 0.7 versus 5.9 ± 1.0 mm; p = 0.031). The mydriatic durability was also better after posterior injection (p = 0.004-0.041).
Apart from immediately after the injection, the initial mydriatic response was similar with both injection techniques, but the durability of the mydriasis was slightly better after a posterior chamber injection of ICM.
比较前房和后房内注射房水内麻醉剂（intracameral mydriatics）对常规超声乳化白内障手术中瞳孔散大效果的影响。
本研究经患者知情同意后，纳入 44 例行单侧超声乳化白内障手术的患者。在手术开始时，通过注射 150μl 的 1.5%苯肾上腺素和 1.0%利多卡因混合液来实现散瞳。患者被随机分配到前房或后房注射组。在手术过程中拍摄瞳孔的照片，并由独立观察者从视频记录中以预定的时间间隔测量平均瞳孔直径。
注射后即刻，后房注射组的瞳孔更大（3.8±0.8mm 比 3.1±0.7mm；p=0.004）。在超声乳化过程后也观察到类似的差异（6.4±0.7mm 比 5.9±1.0mm；p=0.031）。后房注射的散瞳维持时间也更长（p=0.004-0.041）。
除了注射后即刻，两种注射技术的初始散瞳反应相似，但后房内注射 ICM 的散瞳维持时间略长。
