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初诊代谢综合征患者的一年随访:一项观察性研究。

One year follow-up of patients with screen-detected metabolic syndrome in primary care: an observational study.

机构信息

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Fam Pract. 2013 Feb;30(1):40-7. doi: 10.1093/fampra/cms052. Epub 2012 Sep 10.

Abstract

BACKGROUND

Early detection and appropriate treatment of metabolic syndrome (MetS) can modify cardiometabolic risk factors and prevent cardiovascular disease. Optimal screening outcomes require follow-up management of MetS.

OBJECTIVE

To investigate the natural course of events in the first year after positive screening for MetS in primary care with regard to follow-up behavior, medication prescription and lifestyle changes.

METHODS

Screening of 1721 apparently healthy primary care patients (20-70 years old) detected 473 new MetS cases. These people were asked to contact their general practice for subsequent advice and treatment. Data about follow-up behavior of the screening participants and prescription of cardiovascular medication were collected from the electronic medical file, and changes in lifestyle were collected by the practice nurse.

RESULTS

Of the 424 participants with screen-detected MetS for whom data about follow-up were available, 306 (72.2%) spontaneously contacted the practice. Antihypertensive, lipid-lowering and blood glucose-lowering medications were prescribed in 21.5%, 21.2% and 1.9% of the participants, respectively. Half of the participants for whom data about self-reported lifestyle changes were available reported to have increased their physical activity; 16.9% of the smokers quit smoking. Average weight loss was 2.1kg.

CONCLUSIONS

Screening for MetS followed by the advice to contact the general practice for lifestyle counseling and treatment had a substantial spontaneous follow-up. Although the changes in physical activity, weight loss and smoking abstinence are promising, further research will have to demonstrate whether they are sustainable.

摘要

背景

早期发现和适当治疗代谢综合征(MetS)可以改变心血管代谢危险因素,预防心血管疾病。最佳的筛查结果需要对 MetS 进行后续管理。

目的

调查在初级保健中进行 MetS 阳性筛查后的第一年中,关于随访行为、药物处方和生活方式改变的自然病程。

方法

对 1721 名看似健康的初级保健患者(20-70 岁)进行筛查,发现了 473 例新的 MetS 病例。这些人被要求联系他们的全科医生进行后续咨询和治疗。从电子病历中收集了筛查参与者的随访行为和心血管药物处方的数据,并由执业护士收集了生活方式改变的数据。

结果

在有随访数据的 424 名因筛查而患有 MetS 的参与者中,有 306 名(72.2%)自发联系了诊所。分别有 21.5%、21.2%和 1.9%的参与者接受了抗高血压、降脂和降血糖药物治疗。在有自我报告生活方式改变数据的参与者中,有一半报告增加了体力活动;16.9%的吸烟者戒烟。平均体重减轻了 2.1kg。

结论

对 MetS 进行筛查,然后建议联系全科医生进行生活方式咨询和治疗,有大量的自发随访。尽管体力活动、体重减轻和戒烟的变化很有希望,但还需要进一步的研究来证明它们是否可持续。

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