Endocrinology and Metabolism Section, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA, 71130, USA.
Pituitary. 2013 Sep;16(3):351-3. doi: 10.1007/s11102-012-0431-7.
Literature on hyperprolactinemia in the setting of a nipple piercing is limited to individuals with concomitant breast/chest wall infection. It is unclear if chronic nipple stimulation from a piercing alone can cause sustained elevations of serum prolactin. Nipple piercing is emerging as a more mainstream societal form of body art, and the answer to this clinical question would potentially alter patient management. Our aim was to assess serum prolactin levels in subjects with nipple piercing. Inclusion criteria were as follows: men and women ≥ 18 years old with nipple piercing(s) present > 6 months. Exclusion criteria included: women who are pregnant, lactating or < 6 months postpartum; subjects on medications known to increase prolactin levels; chest wall/breast infection at the time of phlebotomy or conditions known to be associated with hyperprolactinemia. Three men and eight women were enrolled. Median (range) ages for men and women were 33 (24-42) and 27 years (23-42), respectively. All except one subject had bilateral piercings. The median interval from nipple piercing to blood draw was 4.0 (2.0-12.0) years. None of the subjects had hyperprolactinemia. Median (range) prolactin levels for men and women were 5.6 ng/mL (3.8-7.4) and 8.0 ng/mL (2.8-10.9), respectively. Our results suggest that in the absence of any concomitant infection, chronic nipple piercing is not associated with hyperprolactinemia.
文献中关于乳头穿孔时高催乳素血症的情况仅限于同时伴有乳房/胸壁感染的个体。目前尚不清楚单独的乳头穿孔引起的慢性乳头刺激是否会导致血清催乳素持续升高。乳头穿孔作为一种更为流行的社会形式的身体艺术，这个临床问题的答案可能会改变患者的管理方式。我们的目的是评估有乳头穿孔的受试者的血清催乳素水平。纳入标准如下：年龄≥18 岁的男性和女性，有乳头穿孔（多个）>6 个月。排除标准包括：怀孕、哺乳期或产后<6 个月的女性；正在服用已知会增加催乳素水平的药物；穿刺时存在胸壁/乳房感染或已知与高催乳素血症相关的疾病。共纳入 3 名男性和 8 名女性。男性和女性的中位（范围）年龄分别为 33（24-42）岁和 27 岁（23-42）。除 1 例外，所有受试者均有双侧穿孔。从乳头穿孔到采血的中位时间间隔为 4.0（2.0-12.0）年。所有受试者均无高催乳素血症。男性和女性的中位（范围）催乳素水平分别为 5.6ng/ml（3.8-7.4）和 8.0ng/ml（2.8-10.9）。我们的结果表明，在没有任何伴随感染的情况下，慢性乳头穿孔与高催乳素血症无关。
