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托珠单抗治疗巨细胞动脉炎:惊人的疗效。

Tocilizumab for giant cell arteritis: an amazing result.

机构信息

Division of Rheumatology, Department of Internal Medicine, Hacettepe University Hospital, Sihhiye, 06100, Ankara, Turkey,

出版信息

Rheumatol Int. 2013 Nov;33(11):2961-2. doi: 10.1007/s00296-012-2516-z. Epub 2012 Sep 11.

Abstract

Giant cell arteritis (GCA), previously Horton's disease, is a systemic vasculitis affecting the middle-sized or large arteries in patients older than 50 years of age. The mainstay of the treatment of GCA is glucocorticoid therapy. Herein, we present a case with giant cell arteritis resistant to oral and intravenous steroid, intravenous cyclophosphamide and mycophenolate mofetil, but successfully treated with tocilizumab.

摘要

巨细胞动脉炎(GCA),以前称为 Horton 病,是一种系统性血管炎,影响 50 岁以上患者的中等或大动脉。GCA 的主要治疗方法是糖皮质激素治疗。在此,我们报告了一例对口服和静脉类固醇、静脉环磷酰胺和霉酚酸酯耐药的巨细胞动脉炎,但成功地用托珠单抗治疗。

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