Guan Yong-Song, He Qing, Wang Ming-Quan
Department of Oncology, West China Hospital of Sichuan University, Chengdu 610041, China.
ISRN Gastroenterol. 2012;2012:480650. doi: 10.5402/2012/480650. Epub 2012 Aug 26.
Transcatheter arterial chemoembolization (TACE) is a minimally invasive technique to treat liver tumors, particularly hepatocellular carcinoma (HCC). TACE was used in early times to treat liver tumor patients with emergencies caused by symptomatic humoral hypercalcemia and develops gradually from the procedures of diagnostic angiography and transcatheter injection of agents and is in particular performed in the treatment of HCC. Since the beginning of this century, TACE has been used extensively in the palliative treatment of unresectable HCC. In recent years, it is indicated in selected patients with early-stage HCC. This review introduces the evolution of TACE for more than 30 years, its role in comprehensive treatment of HCC, the tendency of its refinement in future, and the combination use of TACE with other local ablative methods for the curative result of HCC.
经动脉化疗栓塞术(TACE)是一种治疗肝脏肿瘤,特别是肝细胞癌(HCC)的微创技术。TACE早期用于治疗因症状性体液高钙血症引起紧急情况的肝脏肿瘤患者,它从诊断性血管造影和经导管注射药物的操作逐渐发展而来,尤其用于HCC的治疗。自本世纪初以来,TACE已广泛应用于不可切除HCC的姑息治疗。近年来,它也适用于部分早期HCC患者。本文综述了TACE三十多年来的发展历程、其在HCC综合治疗中的作用、未来精细化的趋势,以及TACE与其他局部消融方法联合使用对HCC的治疗效果。