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意外静脉注射甲哌卡因后用于心脏急救的体外膜肺氧合

ECMO for Cardiac Rescue after Accidental Intravenous Mepivacaine Application.

作者信息

Froehle Michael, Haas Nikolaus A, Kirchner Guenther, Kececioglu Deniz, Sandica Eugen

机构信息

Zentrum angeborener Herzfehler, Herz und Diabetes Zentrum, North-Rhine Westphalia, Georgstrasse 11, 32545 Bad Oeynhausen, Germany.

出版信息

Case Rep Pediatr. 2012;2012:491692. doi: 10.1155/2012/491692. Epub 2012 Aug 27.

Abstract

Mepivacaine is a potent local anaesthetic and used for infiltration and regional anaesthesia in adults and pediatric patients. Intoxications with mepivacaine affect mainly the CNS and the cardiovascular system. We present a case of accidental intravenous mepivacaine application and intoxication of an infant resulting in seizure, broad complex bradyarrhythmia, arterial hypotension and finally cardiac arrest. The patient could be rescued by prolonged resuscitations and a rapid initiation of ECMO and survived without neurological damage. The management strategies of this rare complication including promising other treatment options with lipid emulsions are discussed.

摘要

甲哌卡因是一种强效局部麻醉剂,用于成人和儿科患者的浸润麻醉和区域麻醉。甲哌卡因中毒主要影响中枢神经系统和心血管系统。我们报告一例婴儿意外静脉注射甲哌卡因并中毒的病例,导致癫痫发作、宽QRS波心动过缓、动脉低血压,最终心脏骤停。通过长时间的复苏和迅速启动体外膜肺氧合(ECMO),患者得以获救,且未遗留神经损伤。本文讨论了这种罕见并发症的处理策略,包括其他有前景的脂质乳剂治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fd1/3433119/02ead7097dd3/CRIM.PEDIATRICS2012-491692.001.jpg

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