Univ Franche-Comté, F-25000 Besançon, France; CHU Besançon, Pôle Pharmaceutique, F-25000 Besançon, France.
Talanta. 2012 Sep 15;99:580-5. doi: 10.1016/j.talanta.2012.06.038. Epub 2012 Jun 20.
In this paper, an effective and simple method was used for the immobilization of single wall carbon nanotubes (SWCNTs) on a monolithic HPLC material containing 2 μm macropore sizes and 13 nm mesopore sizes. The chromatographic support was coated with ultra short SWCNTs in a noncovalent way to preserve the sp(2) nanotube structure and thus their physico-chemical properties. It was demonstrated that the amino-surface of the monolith stabilized with 1-methyl-2-pyrrolidinone efficiently and stably adsorbed SWCNTs onto the chromatographic support. It was shown that this novel stationary phase was very useful for the HPLC isocratic mode separation of a series of small aromatic compounds in a very short analysis time. The comparison with a classical equivalent C18 monolithic column showed that the SWCNT column presented the best efficiency in similar chromatographic conditions.
本文采用一种有效而简单的方法，将单壁碳纳米管（SWCNTs）固定在含有 2μm 大孔和 13nm 介孔的整体式 HPLC 材料上。通过非共价方式将超短 SWCNTs 涂覆在色谱支撑体上，以保持 sp(2)纳米管结构及其物理化学性质。实验证明，用 1-甲基-2-吡咯烷酮稳定的氨基表面可将 SWCNTs 有效地、稳定地吸附到色谱支撑体上。结果表明，这种新型固定相非常适用于在非常短的分析时间内以等度模式分离一系列小芳香族化合物。与经典的等效 C18 整体柱相比，SWCNT 柱在相似的色谱条件下呈现出最佳的效率。
