Peters J M, van Marle J, Ariëns A T
Acta Endocrinol Suppl (Copenh). 1979;228:1-190.
The mammogenic and lactogenic effect of various hormones on rat mammary gland has been studied in vitro using an organ culture technique. The effects have been assessed mainly by light microscopy. The study has been confined mainly to the effects and interactions of the lactogenic protein hormones, corticosteroids and progesterone. It establishes the importance of the presence of insulin and serum and of the type of serum for the hormonal effects in vitro. These effects have been studied mainly on the explants obtained from 13 days pregnant rats. In addition explants from non-pregnant rats and at various stages of pregnancy and lactation were studied.
利用器官培养技术在体外研究了各种激素对大鼠乳腺的生乳和泌乳作用。主要通过光学显微镜评估这些作用。该研究主要局限于泌乳蛋白激素、皮质类固醇和孕酮的作用及相互作用。它确定了胰岛素和血清的存在以及血清类型对体外激素作用的重要性。这些作用主要在从怀孕13天的大鼠获取的外植体上进行了研究。此外,还研究了来自未怀孕大鼠以及处于怀孕和泌乳不同阶段的大鼠的外植体。