Weintraub W S, Jones E L, King S B, Craver J, Douglas J S, Guyton R, Liberman H, Morris D
Division of Cardiology, Emory University Hospital, Atlanta, Georgia 30322.
Am J Cardiol. 1990 Jan 15;65(3):183-8. doi: 10.1016/0002-9149(90)90082-c.
Changes in the use of coronary artery bypass grafting (CABG) and percutaneous transluminal coronary angioplasty (PTCA) over the last several years have resulted in a new and different environment for the interventional treatment of coronary artery disease. This study explores these changes as applied to the treatment of chronic coronary artery disease. The study population comprised 14,078 patients undergoing diagnostic cardiac catheterization between 1981 and 1988. In 1981, 1,704 patients underwent a first known cardiac catheterization at Emory University Hospital or Crawford W. Long Hospital and were found to have significant coronary artery disease. Of these patients, 51.7% were treated medically, 44.0% by CABG and 4.3% with PTCA. A similar group comprised 1,719 patients in 1988. Of this group 41.2% were treated medically, 28.5% with CABG and 30.3% with PTCA. The data reveal a much more complex phenomenon than a simple increase in PTCA for the treatment of coronary disease at the expense of CABG. The CABG group aged such that the percent of the CABG population more than 65 years old increased from 26.0% of the total in 1981 to 44.9% of the total in 1988. The percent of patients with ejection fractions less than 50% in the CABG population increased from 24.5% in 1981 to 29.7% in 1988. The PTCA population had less severe disease, was younger and had better left ventricular function.(ABSTRACT TRUNCATED AT 250 WORDS)
在过去几年中,冠状动脉旁路移植术(CABG)和经皮腔内冠状动脉成形术(PTCA)的使用变化,为冠状动脉疾病的介入治疗带来了全新且不同的环境。本研究探讨了这些变化在慢性冠状动脉疾病治疗中的应用。研究人群包括1981年至1988年间接受诊断性心导管插入术的14078例患者。1981年,1704例患者在埃默里大学医院或克劳福德·W·朗医院首次接受已知的心导管插入术,被发现患有严重冠状动脉疾病。在这些患者中,51.7%接受药物治疗,44.0%接受CABG治疗,4.3%接受PTCA治疗。1988年有1719例患者组成类似的一组。该组中41.2%接受药物治疗,28.5%接受CABG治疗,30.3%接受PTCA治疗。数据揭示了一个比以牺牲CABG为代价单纯增加PTCA治疗冠心病更为复杂的现象。CABG组患者年龄增大,65岁以上CABG患者占总人数的百分比从1981年的26.0%增至1988年的44.9%。CABG组中射血分数低于50%的患者百分比从1981年的24.5%增至1988年的29.7%。PTCA组患者病情较轻,年龄较小,左心室功能较好。(摘要截短于250词)