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玻璃体内注射雷珠单抗后发生外源性G组链球菌眼内炎。

Exogenous group G Streptococcus endophthalmitis following intravitreal ranibizumab injection.

作者信息

Kugu Suleyman, Sevim Mehmet Sahin, Kaymak Nilufer Zorlutuna, Erdogan Gurkan, Kandemir Baran, Dogan Omer Kamil

机构信息

Lutfi Kırdar Kartal Training and Research Hospital, Eye Clinic, Istanbul.

出版信息

Clin Ophthalmol. 2012;6:1399-402. doi: 10.2147/OPTH.S31721. Epub 2012 Aug 28.

DOI:10.2147/OPTH.S31721
PMID:22969285
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3437953/
Abstract

We report a case of group G Streptococcus endophthalmitis following an intravitreal ranibizumab injection for a choroidal neovascular membrane. Pars plana vitrectomy was applied for endophthalmitis and group G Streptococcus cultures were isolated in the vitreous samples taken from the patient. Twenty-four hours following pars plana vitrectomy the patient underwent myocardial infarction and cardiac arrest. To our knowledge this is the first reported case of group G Streptococcus endophthalmitis following an intravitreal injection.

摘要

我们报告了1例玻璃体内注射雷珠单抗治疗脉络膜新生血管膜后发生的G群链球菌性眼内炎病例。针对眼内炎进行了玻璃体切割术，从患者采集的玻璃体样本中分离出G群链球菌培养物。玻璃体切割术后24小时，患者发生心肌梗死和心脏骤停。据我们所知，这是首次报道的玻璃体内注射后发生G群链球菌性眼内炎的病例。

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Int J Inflam. 2012;2012:313248. doi: 10.1155/2012/313248. Epub 2012 Feb 22.
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Bilateral same-day intravitreal injections using a single vial and molecular bacterial screening for safety surveillance.双侧同日玻璃体腔内注射，使用单瓶药物，并进行分子细菌筛查以进行安全性监测。
Retina. 2012 Apr;32(4):667-71. doi: 10.1097/IAE.0b013e31822c296b.
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Bilateral intravitreal injection of antivascular endothelial growth factor therapy.双侧玻璃体内注射抗血管内皮生长因子治疗。
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Case of endogenous endophthalmitis caused by Streptococcus equisimilis.马链球菌似马亚种引起的内源性眼内炎病例。
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