Department of Paediatric Dentistry, Guilan Dental School, Rasht, Iran.
Haemophilia. 2013 Jan;19(1):65-70. doi: 10.1111/hae.12002. Epub 2012 Sep 13.
The purpose of this study was to investigate the dental and some other aspects of oral health status of young patients with congenital bleeding disorders (CBD) and the impact of these on their quality of life (OHR-QoL) compared with controls. DMFS-dmfs (Decayed, Missed, Filled Tooth surfaces in permanent and primary teeth) scores, Simplified oral hygiene index, occurance of hypoplasia of first permanent molars, Temporomandibular joint dysfunction and occlusion of 46 CBD patients at the age range of 2-15 years and 46 of other children as control were compared, and the impact of their oral health situation on quality of life was also investigated. Data were analysed by chi-square, t-test and Pearson correlation. Patients were significantly more caries-free with less decayed teeth in primary-permanent dentition (P = 0.03, t = -2.17).The mean scores of OHR-QoL of CBD patients and controls were not significantly different. Oral Bleeding was the significant variable in relation to 'oral health-related quality of life' in CBD groups (Pearson correlation, r = -0.56, P = 0.000). OHR-QoL in the control group was related to dmfs score (r = -0.392, P = 0.011) and male gender (r = -0.329, P = 0.026). Congenital bleeding disorder CBD patients were found to have a better dental health situation in primary dentition compared with controls; however, their 'oral health-related quality of life' was similar. Oral bleeding was the only significant factor related to OHR-QoL in CBD. It shows an overall importance of development of comprehensive care centres for CBD as the main cause of this achievement.
本研究旨在调查先天性出血性疾病 (CBD) 年轻患者的口腔健康状况，包括牙齿及其他方面，并与对照组进行比较，以评估这些因素对生活质量（OHR-QoL）的影响。我们比较了 46 名年龄在 2-15 岁 CBD 患者和 46 名对照组儿童的 DMFS-dmfs（恒牙和乳牙龋齿、缺失、填充牙面）评分、简化口腔卫生指数、第一恒磨牙发育不全、颞下颌关节功能紊乱和咬合情况，并探讨了他们的口腔健康状况对生活质量的影响。采用卡方检验、t 检验和 Pearson 相关性分析数据。结果显示，与对照组相比，CBD 患者的原发性和永久性牙齿中龋齿较少，无龋齿率更高（P = 0.03，t = -2.17）。CBD 患者和对照组的 OHR-QoL 平均评分无显著差异。口腔出血是 CBD 组中与“口腔健康相关生活质量”显著相关的变量（Pearson 相关性，r = -0.56，P = 0.000）。对照组的 OHR-QoL 与 dmfs 评分（r = -0.392，P = 0.011）和男性性别（r = -0.329，P = 0.026）相关。与对照组相比，先天性出血性疾病 CBD 患者的原发性牙齿健康状况较好，但“口腔健康相关生活质量”相似。口腔出血是 CBD 患者 OHR-QoL 相关的唯一显著因素。这表明建立全面的 CBD 综合护理中心具有重要意义，这也是取得这一成就的主要原因。
