子痫前期合并妊娠后十年、三十年及终身心血管疾病风险评估。
Ten-year, thirty-year, and lifetime cardiovascular disease risk estimates following a pregnancy complicated by preeclampsia.
作者信息
Smith Graeme N, Pudwell Jessica, Walker Mark, Wen Shi-Wu
机构信息
Department of Obstetrics & Gynaecology, Kingston General Hospital, Queen's University, Kingston ON; Department of Biomedical and Molecular Sciences, Kingston General Hospital, Queen's University, Kingston ON.
Department of Obstetrics and Gynecology, Ottawa Health Research Institute, University of Ottawa, Ottawa ON.
出版信息
J Obstet Gynaecol Can. 2012 Sep;34(9):830-835. doi: 10.1016/S1701-2163(16)35381-6.
OBJECTIVE
To calculate the cardiovascular disease (CVD) risk estimates for women following a pregnancy with or without preeclampsia.
METHODS
We calculated 10-year, 30-year, and lifetime CVD risk estimates at one year postpartum for women recruited into the Pre-Eclampsia New Emerging Team's prospective cohort.
RESULTS
Complete CVD risk screening data were obtained from 118 control women and 99 preeclamptic women. A total of 18.2% of preeclamptic women and 1.7% of control women had a high 10-year risk (OR 13.08; 95% CI 3.38 to 85.5), 31.3% of preeclamptic women and 5.1% of control women had a high 30-year risk (OR 8.43; 95% CI 3.48 to 23.23), and 41.4% of preeclamptic women and 17.8% of control women had a high lifetime risk for CVD (OR 3.25; 95% CI 1.76 to 6.11).
CONCLUSIONS
The association of preeclampsia with the future development of CVD makes pregnancy an early window of opportunity for the preservation of health and prevention of CVD.
目的
计算患或未患子痫前期的女性在妊娠后发生心血管疾病（CVD）的风险估计值。
方法
我们对纳入子痫前期新兴团队前瞻性队列研究的女性，在产后一年计算其10年、30年和终生CVD风险估计值。
结果
从118名对照女性和99名子痫前期女性中获得了完整的CVD风险筛查数据。共有18.2%的子痫前期女性和1.7%的对照女性有较高的10年风险（比值比13.08；95%置信区间3.38至85.5），31.3%的子痫前期女性和5.1%的对照女性有较高的30年风险（比值比8.43；95%置信区间3.48至23.23），41.4%的子痫前期女性和17.8%的对照女性有较高的终生CVD风险（比值比3.25；95%置信区间1.76至6.11）。
结论
子痫前期与CVD未来发展之间的关联使得妊娠成为维护健康和预防CVD的一个早期机会窗口。
Zotero 插件