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[在视路后部手术中通过硬膜下电极连续监测皮层视觉诱发电位。病例报告及文献复习]

[Continuous monitoring of cortical visual evoked potentials by means of subdural electrodes in surgery on the posterior optic pathway. A case report and review of the literature].

作者信息

Torres Cristina V, Pastor Jesús, Rocío Esmeralda, Sola Rafael G

机构信息

Servicio de Neurocirugía, Hospital Universitario de la Princesa, 28006 Madrid, España.

出版信息

Rev Neurol. 2012 Sep 16;55(6):343-8.

Abstract

INTRODUCTION

Intraoperative monitoring of functional language and motor areas is a commonly used technique which makes it possible to minimise the post-operative sequelae and to perform an optimal resection of lesions in these areas. Monitoring of the visual cortex, however, is not usually carried out nowadays. The scarce spatial resolution and its sensitivity to anaesthesia are some of the technical difficulties that reduce its clinical usefulness. The study reports a case of resection of an occipital lesion under general anaesthetic, with intraoperative monitoring of the cortical visual evoked potentials (VEP) by means of subdural electrodes.

CASE REPORT

A 50-year-old female who underwent surgery involving the resection of an occipital lesion that was suggestive of radionecrosis. The VEP were monitored by administering flashing light at 4.1 Hz and recording with subdural strip electrodes on the occipital cortex. During the operation, a progressive lowering of the amplitude of the cortical VEP was observed when 50% of the baseline amplitude was exceeded, and thus the resection was finished. The increase in latency was below 10% of the baseline value. The patient recovered well during the post-operative period and her sight did not present any changes with respect to the baseline values.

CONCLUSIONS

In our case, monitoring the cortical VEP by cortical recordings produced stable recordings with a good correlation with the post-operative visual function. Cortical recordings performed either directly or by means of subdural electrodes make it possible to achieve adequate spatial resolution and response intensity. Further studies need to be conducted with a greater number of patients in order to obtain decisive conclusions.

摘要

引言

术中对功能语言区和运动区进行监测是一种常用技术,它能够将术后后遗症降至最低,并对这些区域的病变进行最佳切除。然而,目前通常不对视觉皮层进行监测。空间分辨率不足及其对麻醉的敏感性是降低其临床实用性的一些技术难题。本研究报告了一例在全身麻醉下切除枕叶病变的病例,术中通过硬膜下电极对皮层视觉诱发电位(VEP)进行监测。

病例报告

一名50岁女性接受了手术,切除一个提示放射性坏死的枕叶病变。通过以4.1赫兹的频率给予闪光并使用枕叶皮层上的硬膜下条形电极进行记录来监测VEP。手术过程中,当超过基线振幅的50%时,观察到皮层VEP的振幅逐渐降低,于是手术结束。潜伏期的增加低于基线值的10%。患者术后恢复良好,其视力与基线值相比没有任何变化。

结论

在我们的病例中,通过皮层记录监测皮层VEP产生了稳定的记录,与术后视觉功能具有良好的相关性。直接或通过硬膜下电极进行的皮层记录能够实现足够的空间分辨率和反应强度。需要对更多患者进行进一步研究以得出决定性结论。

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