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在食管癌、乳腺癌和头颈癌近距离放射治疗期间,印度参考成人的计算机体层摄影器官剂量。

Computed organ doses to an Indian reference adult during brachytherapy treatment of esophagus, breast, and neck cancers.

作者信息

Keshavkumar Biju

机构信息

Health Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.

出版信息

J Med Phys. 2012 Jul;37(3):151-4. doi: 10.4103/0971-6203.99238.

Abstract

This study aims to generate the normalized mean organ dose factors (mGy min(-1) GBq(-1)) to healthy organs during brachytherapy treatment of esophagus, breast, and neck cancers specific to the patient population in India. This study is in continuation to the earlier published studies on the estimation of organ doses during uterus brachytherapy treatments. The results are obtained by Monte Carlo simulation of radiation transport through MIRD type anthropomorphic mathematical phantom representing reference Indian adult with (192)Ir and (60)Co high dose rate sources in the esophagus, breast, and neck of the phantom. The result of this study is compared with a published computational study using voxel-based phantom model. The variation in the organ dose of this study to the published values is within 50%.

摘要

本研究旨在针对印度患者群体,生成在食管癌、乳腺癌和头颈癌近距离放射治疗期间,健康器官的归一化平均器官剂量因子(毫戈瑞每分钟每吉贝可,mGy min⁻¹ GBq⁻¹)。本研究是对先前发表的关于子宫近距离放射治疗期间器官剂量估计研究的延续。通过蒙特卡罗模拟辐射在代表印度成年参考人体模型(MIRD型人体数学模型)中的传输来获得结果,该模型在人体模型的食管、乳房和颈部含有¹⁹²Ir和⁶⁰Co高剂量率源。本研究结果与一项使用基于体素的人体模型的已发表计算研究进行了比较。本研究中器官剂量与已发表值的差异在50%以内。

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