Kotb Af, Alkosiry M, Abdelkawy N, Atta Ma
Faculty of Medicine, Alexandria University, Al-Kartoum Square, Alexandria, Egypt.
Ecancermedicalscience. 2012;6:268. doi: 10.3332/ecancer.2012.268. Epub 2012 Sep 13.
Bladder cancer represents a considerable issue in Egypt and the Middle East. Radical cystectomy and orthotopic neobladder represent the standard of care for managing cases with invasive bladder tumour. There are few cases reported in the literature considering the urothelial recurrence in the urethra, connected to neobladder. We are presenting a rare case of a young female patient, with an aggressive urothelial tumour, recurring 13-year post-radical cystectomy, and the Studer neobladder. Our case was managed by urethrectomy and conversion of the neobladder into continent reservoir, with good short-term oncological and functional outcomes. We can conclude that bladder cancer cases should be followed thoroughly throughout their life. Follow-up urethroscopy and cytology should be done for all cases of post-radical cystectomy, regardless of patients' symptoms.
Late urothelial recurrence of post-radical cystectomy is possible and, in our case, happened 13 years following surgery. The Studer neobladder can be safely converted into continent reservoir, allowing good functional outcomes. Also, recurrence in the Studer neobladder can be safely managed, allowing good oncological outcomes, without the need for any ureteroileal interventions.
膀胱癌在埃及和中东地区是一个相当严重的问题。根治性膀胱切除术和原位新膀胱术是治疗浸润性膀胱肿瘤病例的标准治疗方法。文献中报道的与新膀胱相关的尿道尿路上皮复发病例很少。我们报告了一例年轻女性患者的罕见病例,她患有侵袭性尿路上皮肿瘤,在根治性膀胱切除术后13年复发,采用的是施图德新膀胱术。我们的病例通过尿道切除术并将新膀胱转换为可控储尿囊进行治疗,短期肿瘤学和功能结果良好。我们可以得出结论,膀胱癌病例应终身进行全面随访。对于所有根治性膀胱切除术后的病例,无论患者有无症状,都应进行随访尿道镜检查和细胞学检查。
根治性膀胱切除术后尿路上皮晚期复发是可能的,在我们的病例中,发生在手术后13年。施图德新膀胱可以安全地转换为可控储尿囊,功能结果良好。此外,施图德新膀胱的复发也可以安全地处理,肿瘤学结果良好,无需任何输尿管回肠干预。