Bhattacharyya S, Roy S, Mukhopadhyay Pk, Rit K, Dey Jb, Ganguly U, Ray R
Department of Microbiology, Bankura Sammilani Medical College, Bankura, West Bengal, India.
Iran J Microbiol. 2012 Jun;4(2):98-9.
Staphylococcus aureus produces a particular morphological variant called small colony variant (SCV) which is responsible for persistent subclinical infections in predisposed individuals and is usually resistant to aminoglycosides and cell wall active antibiotics. Infections by SCV of S. aureus are an upcoming problem due to difficulty in laboratory diagnosis and resistance to antimicrobial chemotherapy. We here report a case of infective endocarditis caused by SCV of Staphylococcus aureus in a pediatric patient.
金黄色葡萄球菌会产生一种特殊的形态变异体,称为小菌落变异体(SCV),它会导致易感个体发生持续性亚临床感染,并且通常对氨基糖苷类药物和细胞壁活性抗生素耐药。由于实验室诊断困难以及对抗菌化疗耐药,金黄色葡萄球菌SCV引起的感染正成为一个新出现的问题。我们在此报告一例儿科患者由金黄色葡萄球菌SCV引起的感染性心内膜炎病例。