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利用以基层医疗为基础的丙型肝炎诊所,改善城市中服务不足人群获得丙型肝炎治疗的机会。

Improving access to hepatitis C care for urban, underserved patients using a primary care-based hepatitis C clinic.

机构信息

Division of General Medicine, Emory University School of Medicine, Atlanta, Georgia 0303, USA.

出版信息

J Natl Med Assoc. 2012 May-Jun;104(5-6):244-50. doi: 10.1016/s0027-9684(15)30161-9.

Abstract

OBJECTIVE

Chronic hepatitis C affects 200 million people worldwide and is a leading cause of death from liver disease. Effective treatment is available but can be difficult to access for uninsured, urban patients. National organizations have called for improving access to hepatitis C care in these groups. We present an innovative model for expanding access to hepatitis C care for urban, underserved patients (The Grady Liver Clinic, Grady Memorial Hospital, Atlanta, Georgia). The liver clinic provides hepatitis C care by general internists in the primary care setting.

METHODS

We performed a retrospective chart review of all liver clinic patients (n=807) who presented in the first 5 years of the clinic's operation. Measures included patients' demographic and hepatitis C-related characteristics; prevalence of medical, psychiatric, and substance abuse comorbidities; and treatment status.

RESULTS

The liver clinic population is primarily black (76%) and uninsured (59%). Patients had difficult-to-treat characteristics, including genotype 1 hepatitis C (90%), advanced liver fibrosis (28%), and high viral loads. Sixty-seven percent had comorbid medical conditions, and 40% had psychiatric disease. Fourteen percent of patients were treated for hepatitis C during the study period.

CONCLUSION

The liver clinic has proven to be a successful model for improving access to hepatitis C care for urban, underserved patients. Despite having significant hepatic disease and medical and psychiatric comorbidities, patients in the liver clinic can be successfully maintained in care and initiated on hepatitis C treatment by general internists in a primary care setting.

摘要

目的

全球有 2 亿人患有慢性丙型肝炎,它是导致肝病死亡的主要原因。虽然已有有效的治疗方法,但对于没有保险的城市患者来说,获得治疗可能较为困难。为此,一些国家组织呼吁改善这些人群获得丙型肝炎治疗的机会。我们提出了一种创新模式,旨在为城市中服务不足的丙型肝炎患者扩大获得治疗的机会(格鲁迪肝脏诊所,格鲁迪纪念医院,亚特兰大,佐治亚州)。该肝脏诊所由初级保健环境中的普通内科医生提供丙型肝炎护理。

方法

我们对肝脏诊所运营的前 5 年内就诊的所有肝脏诊所患者(n=807)进行了回顾性病历审查。评估指标包括患者的人口统计学和丙型肝炎相关特征;并存的医疗、精神和药物滥用共病的患病率;以及治疗状况。

结果

肝脏诊所的就诊人群主要是黑人(76%)和没有保险的人(59%)。患者具有难以治疗的特征,包括丙型肝炎基因型 1(90%)、晚期肝纤维化(28%)和高病毒载量。67%的患者有并存的医疗状况,40%的患者有精神疾病。在研究期间,有 14%的患者接受了丙型肝炎治疗。

结论

肝脏诊所已被证明是为城市中服务不足的丙型肝炎患者改善获得治疗机会的成功模式。尽管存在严重的肝脏疾病和医疗及精神共病,但初级保健环境中的普通内科医生可以成功地为肝脏诊所的患者提供护理,并为他们启动丙型肝炎治疗。

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