Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Clin Radiol. 2012 Dec;67(12):e58-63. doi: 10.1016/j.crad.2012.07.020. Epub 2012 Sep 10.
To evaluate the efficacy and efficiency of three-dimensional (3D) fast spin-echo (FSE) with variable flip angle ("CUBE") magnetic resonance imaging (MRI) in knee imaging as compared with conventional MRI.
Twenty-nine patients (single knee) with joint injuries of varying degrees were enrolled in this study between January, 2011 and December, 2011. All patients underwent conventional MRI and a fat-suppressed CUBE MRI sequence. All patients subsequently underwent knee arthroscopic surgery performed by an experienced orthopaedic surgeon within 2 weeks after the MRI examinations. With standard reference provided by arthroscopic results, the sensitivity, specificity, and accuracy of both the CUBE and conventional MRI techniques were calculated for detecting cartilage lesions, meniscus tears, and anterior cruciate ligament injuries, respectively. A chi-square test was used for statistical analysis with a level of significance of p < 0.05.
For the evaluation of articular cartilage lesions, the CUBE sequence had higher sensitivity (70.9% versus 50.6%, p < 0.01), higher specificity (72.6% versus 58.9%, p < 0.05), and higher accuracy (71.8% versus 55.2%, p = 0.001) than conventional MRI. For the evaluation of meniscus tears, CUBE and conventional MRI had similar sensitivity, specificity, and accuracy (p = 0.20-0.55). Similarly, there was no significant difference in sensitivity, specificity, or accuracy between CUBE imaging and conventional imaging in the detection of anterior cruciate ligament injuries (p = 0.13-0.65).
CUBE MRI has similar or superior sensitivity, specificity, and accuracy to a conventional imaging protocol in the comprehensive evaluation of knee joint injuries.
评估三维（3D）快速自旋回波（FSE）可变翻转角（“CUBE”）磁共振成像（MRI）在膝关节成像中的功效和效率，与常规 MRI 相比。
2011 年 1 月至 12 月期间，共纳入 29 例（单膝）关节损伤程度不同的患者。所有患者均行常规 MRI 和脂肪抑制 CUBE MRI 序列检查。所有患者均在 MRI 检查后 2 周内行由经验丰富的骨科医生进行的膝关节关节镜手术。以关节镜检查结果为标准参考，计算 CUBE 和常规 MRI 技术检测软骨病变、半月板撕裂和前交叉韧带损伤的敏感性、特异性和准确性。采用卡方检验进行统计学分析，以 p < 0.05 为差异有统计学意义。
在评估关节软骨病变方面，CUBE 序列的敏感性（70.9%比 50.6%，p < 0.01）、特异性（72.6%比 58.9%，p < 0.05）和准确性（71.8%比 55.2%，p = 0.001）均高于常规 MRI。在评估半月板撕裂方面，CUBE 和常规 MRI 的敏感性、特异性和准确性相似（p = 0.20-0.55）。同样，CUBE 成像与常规成像在检测前交叉韧带损伤方面的敏感性、特异性或准确性也无显著差异（p = 0.13-0.65）。
在膝关节损伤的综合评估中，CUBE MRI 与常规成像方案具有相似或更高的敏感性、特异性和准确性。
