除CYP2C19外，PON1基因变异影响中国患者氯吡格雷治疗后的血小板反应性。 - Suppr

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超能文献

Besides CYP2C19, PON1 genetic variant influences post-clopidogrel platelet reactivity in Chinese patients.

作者信息

Wu Hongyi, Qian Juying, Xu Jianfeng, Sun Aijun, Sun Wenzhu, Wang Qibing, Ge Junbo

出版信息

Int J Cardiol. 2013 Apr 30;165(1):204-6. doi: 10.1016/j.ijcard.2012.08.017. Epub 2012 Sep 11.

DOI:10.1016/j.ijcard.2012.08.017

PMID:22974728

Abstract

摘要

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Besides CYP2C19, PON1 genetic variant influences post-clopidogrel platelet reactivity in Chinese patients.除CYP2C19外，PON1基因变异影响中国患者氯吡格雷治疗后的血小板反应性。

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[Clopidogrel metabolism related gene polymorphisms in Chinese patients with acute coronary syndrome].中国急性冠状动脉综合征患者中氯吡格雷代谢相关基因多态性

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Association of PON1, P2Y12 and COX1 with Recurrent Ischemic Events in Patients with Extracranial or Intracranial Stenting.颅外或颅内支架置入患者中对氧磷酶1、P2Y12和环氧化酶1与复发性缺血事件的关联

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Both PON1 Q192R and CYP2C19*2 influence platelet response to clopidogrel and ischemic events in Chinese patients undergoing percutaneous coronary intervention.在中国接受经皮冠状动脉介入治疗的患者中，PON1 Q192R和CYP2C19*2均会影响血小板对氯吡格雷的反应及缺血事件。

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