Yamagishi Hidetsugu, Sakamoto Taku, Matsuda Takahisa, Nakajima Takeshi, Saito Yutaka
Endoscopy Division, National Cancer Center Hospital, Japan.
Intern Med. 2012;51(17):2321-4. doi: 10.2169/internalmedicine.51.7559. Epub 2012 Sep 1.
We herein present a case of IIc-like metastatic lung cancer that was detected early. A 65-year-old man presented with diarrhea and difficulty walking. Colonoscopy demonstrated a depressed lesion in the descending colon. However, the appearance of the lesion by endoscopy with a magnifying objective was not compatible with early colon cancer. Therefore, we performed diagnostic endoscopic mucosal resection to allow for an examination of the whole lesion. A histological examination demonstrated lung cancer metastasis to the colon. Only 1.6% of lung cancers metastasize to the large intestine, and metastatic colorectal cancer is not usually detected at an early stage. In the present case, however, endoscopy and a histological examination revealed alterations in the mucosal configuration of the lesion, which were unusual for early colon cancer.
我们在此报告一例早期发现的类IIc型转移性肺癌病例。一名65岁男性出现腹泻和行走困难。结肠镜检查显示降结肠有一个凹陷性病变。然而,使用放大物镜的内镜检查发现该病变的外观与早期结肠癌不符。因此,我们进行了诊断性内镜黏膜切除术,以便对整个病变进行检查。组织学检查显示肺癌转移至结肠。仅有1.6%的肺癌会转移至大肠,转移性结直肠癌通常在早期不会被发现。然而,在本病例中,内镜检查和组织学检查发现病变的黏膜形态改变,这在早期结肠癌中并不常见。