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甲型流感感染后出现的眼阵挛-肌阵挛综合征

Opsoclonus-myoclonus syndrome following influenza a infection.

作者信息

Morita Akihiko, Ishihara Masaki, Kamei Satoshi, Ishikawa Hiroshi

机构信息

Division of Neurology, Department of Internal Medicine, Nihon University School of Medicine, Japan.

出版信息

Intern Med. 2012;51(17):2429-31. doi: 10.2169/internalmedicine.51.7627. Epub 2012 Sep 1.

Abstract

A 60-year-old woman developed opsoclonus-myoclonus syndrome (OMS) a week after being diagnosed with influenza A infection by a rapid antigen test. She had no loss of consciousness. Opsoclonus, myoclonus, and truncal ataxia were noted. Two weeks after treatment with intravenous immunoglobulin and corticosteroids, her opsoclonus, myoclonus, and truncal ataxia disappeared. No malignant tumors were detected during the 3-year follow-up period. There has been no previous report of postinfectious OMS following confirmed influenza A infection. OMS without a loss of consciousness has been reported to be statistically less common in cases of non-paraneoplastic OMS. This finding was consistent with the present patient's clinical manifestations.

摘要

一名60岁女性在通过快速抗原检测确诊为甲型流感感染一周后出现眼阵挛-肌阵挛综合征(OMS)。她没有意识丧失。观察到有眼阵挛、肌阵挛和躯干共济失调。在接受静脉注射免疫球蛋白和皮质类固醇治疗两周后,她的眼阵挛、肌阵挛和躯干共济失调消失。在3年的随访期内未检测到恶性肿瘤。此前尚无确诊甲型流感感染后发生感染后OMS的报告。据报道,在非副肿瘤性OMS病例中,无意识丧失的OMS在统计学上不太常见。这一发现与该患者的临床表现相符。

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