用于温度触发药物递送的生物相容磁性脂质体。
Biocompatible magnetic liposomes for temperature triggered drug delivery.
机构信息
Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, PR China.
出版信息
Nanoscale. 2012 Oct 21;4(20):6289-92. doi: 10.1039/c2nr31292a.
PMID:22976154
Abstract
Thermosensitive magnetic liposomes (TSMLs) that serve as carriers for controlled drug release are fabricated. The TSMLs are stable below 39 °C and most drugs (5-(and-6)-carboxylfluorescein: 68% and doxorubicin: 90%) release within 1 h at 42 °C. Furthermore, TSMLs could deliver the anticancer drugs into cells to induce cell apoptosis.
摘要
制备了作为控释药物载体的温敏磁性脂质体（TSML）。TSML 在 39°C 以下稳定，在 42°C 下大多数药物（5-(和-6)-羧基荧光素：68%和阿霉素：90%）在 1 小时内释放。此外，TSML 可以将抗癌药物递送到细胞中诱导细胞凋亡。
Zotero 插件