Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Microsurgery. 2013 Feb;33(2):130-3. doi: 10.1002/micr.22040. Epub 2012 Sep 14.
Lymphaticovenular anastomosis (LVA) is a useful treatment for compression-refractory lymphedema with its effectiveness and minimal invasiveness. However, LVA requires supermicrosurgery, where lymphatic vessels with a diameter of 0.5 mm or smaller are anastomosed using 11-0 or 12-0 suture. To make LVA easier and safer, we adopted a modified side-to-end (S-E) anastomosis in LVA surgery.
We performed modified S-E LVAs in 14 limbs of female patients with lower extremity lymphedema (LEL). In modified S-E LVA, lateral windows with a length of 1.0 mm or longer were created on a lymphatic vessel and a vein, respectively, and side-to-side (S-S) anastomosis was established with 10-0 continuous suture. After completion of S-S anastomosis, the vein distal to the anastomosis site was ligated to prevent venous backflow and subsequent thrombosis at the anastomosis site. Lymphedematous volume was evaluated preoperatively and at postoperative 6 months using LEL index.
All the 24 modified S-E anastomoses could be completed without difficulty or revision for anastomosis, and showed good patency after completion of anastomosis. Postoperatively, LEL indices significantly decreased compared with preoperative LEL index (255.9 ± 14.1 vs. 274.9 ± 22.2, P < 0.001).
Modified S-E LVA can efficaciously divert lymph flows into venous circulation without performing supermicrosurgical anastomosis.
淋巴管静脉吻合术(LVA)是一种治疗压迫性难治性淋巴水肿的有效且微创的方法。然而,LVA 需要超显微手术,即使用 11-0 或 12-0 缝线吻合直径为 0.5 毫米或更小的淋巴管。为了使 LVA 更容易和更安全,我们在 LVA 手术中采用了改良的侧-端(S-E)吻合术。
我们对 14 例下肢淋巴水肿(LEL)女性患者的 14 条肢体进行了改良 S-E LVA。在改良 S-E LVA 中,分别在淋巴管和静脉上创建长度为 1.0 毫米或更长的侧窗,并使用 10-0 连续缝线建立侧-侧(S-S)吻合。完成 S-S 吻合后,结扎吻合部位远端的静脉,以防止静脉回流和随后在吻合部位形成血栓。使用 LEL 指数在术前和术后 6 个月评估淋巴水肿体积。
所有 24 个改良 S-E 吻合均顺利完成,无需进行吻合修正,并且吻合完成后通畅良好。与术前 LEL 指数相比,术后 LEL 指数显著降低(255.9 ± 14.1 比 274.9 ± 22.2,P < 0.001)。
改良 S-E LVA 可以有效地将淋巴液引流到静脉循环中,而无需进行超显微手术吻合。