State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, PR China.
Chemistry. 2012 Oct 22;18(43):13629-32. doi: 10.1002/chem.201202146. Epub 2012 Sep 13.
Single probe, multiple targets: the design and synthesis of a new probe is described that can readily discriminate Zn(2+) and Cd(2+) with different fluorescence signals. The studies of Job's plot, mass spectroscopy, DFT calculations, and (1)H NMR spectroscopy reveal that the new probe has possible distinct binding modes to Zn(2+) and Cd(2+). This work may open up new opportunities for the development of single fluorescent probes that can sense multiple targets of interest.
单探针，多目标：本文描述了一种新探针的设计和合成，该探针可以通过不同的荧光信号轻松区分 Zn(2+)和 Cd(2+)。Job 图、质谱、DFT 计算和 (1)H NMR 光谱研究表明，新探针与 Zn(2+)和 Cd(2+)可能具有不同的结合模式。这项工作可能为开发能够感应多个感兴趣目标的单荧光探针开辟新的机会。
