Centre for Drug Discovery and Conservation, Institute of Applied Sciences, The University of the South Pacific, Suva, Fiji.
Nat Prod Rep. 2012 Dec;29(12):1424-62. doi: 10.1039/c2np20055d. Epub 2012 Sep 14.
Over the past 30 years, approximately 140 papers have been published on marine natural products chemistry and related research from the Fiji Islands. These came about from studies starting in the early 1980s by the research groups of Crews at the University of California Santa Cruz, Ireland at the University of Utah, Gerwick from the Scripps Institution of Oceanography, the University of California at San Diego and the more recent groups of Hay at the Georgia Institute of Technology (GIT) and Jaspars from the University of Aberdeen. This review covers both known and novel marine-derived natural products and their biological activities. The marine organisms reviewed include invertebrates, plants and microorganisms, highlighting the vast structural diversity of compounds isolated from these organisms. Increasingly during this period, natural products chemists at the University of the South Pacific have been partners in this research, leading in 2006 to the development of a Centre for Drug Discovery and Conservation (CDDC).
在过去的 30 年中，约有 140 篇关于斐济海洋天然产物化学及相关研究的论文发表。这些研究始于 20 世纪 80 年代初，加州大学圣克鲁兹分校的克鲁斯（Crews）研究小组、犹他大学的爱尔兰（Ireland）研究小组、斯克里普斯海洋学研究所的杰威克（Gerwick）、加州大学圣地亚哥分校以及最近的佐治亚理工学院（GIT）的海（Hay）研究小组和阿伯丁大学的贾斯帕斯（Jaspars）研究小组都开展了相关研究。这篇综述涵盖了已知和新型海洋衍生天然产物及其生物活性。综述的海洋生物包括无脊椎动物、植物和微生物，突出了从这些生物中分离出的化合物具有广泛的结构多样性。在此期间，南太平洋大学的天然产物化学家越来越多地成为这项研究的合作伙伴，这导致 2006 年成立了药物发现与保护中心（CDDC）。
