Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan.
J R Soc Interface. 2012 Dec 7;9(77):3554-63. doi: 10.1098/rsif.2012.0603. Epub 2012 Sep 12.
The transport properties of Brownian ratchet were studied in the presence of stochastic intensity noise in both overdamped and underdamped regimes. In the overdamped case, an analytical solution using the matrix-continued fraction method revealed the existence of a maximum current when the noise intensity fluctuates on intermediate timescale regions. Similar effects were observed for the underdamped case by Monte Carlo simulations. The optimal time-correlation for Brownian transport coincided with the experimentally observed time-correlation of the extrinsic noise in Escherichia coli gene expression and implied the importance of environmental noise for molecular mechanisms.
布朗棘轮的输运性质在过阻尼和欠阻尼两种情况下的随机强度噪声中进行了研究。在过阻尼情况下，使用矩阵连分式方法的解析解揭示了当噪声强度在中间时间尺度区域波动时存在最大电流的现象。蒙特卡罗模拟在欠阻尼情况下观察到了类似的效应。布朗输运的最佳时间相关与大肠杆菌基因表达中外在噪声的实验观测时间相关相一致，这意味着环境噪声对于分子机制的重要性。
