Singh Saurabh, Kumaraswamy Vinay, Sharma Nitin, Saraf Shyam Kumar, Khare Ghanshyam Narayan
Department of Orthopedics, Institute of Medical Science, Banaras Hindu University, Varanasi, India.
Asian Spine J. 2012 Sep;6(3):183-93. doi: 10.4184/asj.2012.6.3.183. Epub 2012 Aug 21.
Prospective study with simple randomization.
To evaluate the results of anterior spinal instrumentation, debridement and decompression of cord and compare it with results of a similar procedure done without the use of anterior instrumentation.
Use of anterior spinal instrumentation in treatment of tubercular spondylitis is still an infrequently followed modality of treatment and data regarding its usefulness are still emerging.
Thirty-two patients of tubercular paraplegia with involvement of dorsal and dorso-lumbar vertebrae were operated with anterior spinal cord decompression, autofibular strut grafting with anterior instrumentation in 18 patients and no implant in 14 patients. Results were compared on the basis of improvement in Frankel grade, correction of local kyphosis, decrease in canal compromise and further progression of kyphosis.
The mean local kyphosis correction in the immediate postoperative period was 24.1° in the instrumented group and was 6.1° in the non instrumented group. The mean late loss of correction of local kyphosis at 3 years follow-up was 1.7° in the instrumented and 6.7° in the non instrumented group. The mean improvement in canal compression was 39.5% in the instrumented group and 34.8% in the non instrumented group.
In treatment of tubercular spondylitis by anterior debridement and decompression of the spinal cord and autofibular strut grafting, the use of instrumentation has no relation with the improvement in neurological status, however the correction of local kyphosis and prevention of further progression of local kyphosis was better with the use anterior spinal instrumentation.
采用简单随机化的前瞻性研究。
评估前路脊柱内固定、清创及脊髓减压的结果,并将其与未使用前路内固定的类似手术结果进行比较。
前路脊柱内固定在结核性脊柱炎治疗中的应用仍然是一种较少采用的治疗方式,关于其有效性的数据仍在不断涌现。
32例累及胸段和胸腰段椎体的结核性截瘫患者接受了前路脊髓减压手术,18例患者采用自体腓骨支撑植骨并前路内固定,14例患者未植入内固定物。根据Frankel分级的改善情况、局部后凸畸形的矫正、椎管狭窄的减轻以及后凸畸形的进一步进展来比较结果。
术后即刻,内固定组局部后凸畸形的平均矫正角度为24.1°,未内固定组为6.1°。在3年随访时,内固定组局部后凸畸形矫正的平均后期丢失角度为1.7°,未内固定组为6.7°。内固定组椎管压迫的平均改善率为39.5%,未内固定组为34.8%。
在前路清创、脊髓减压及自体腓骨支撑植骨治疗结核性脊柱炎时,内固定的使用与神经功能状态的改善无关,然而使用前路脊柱内固定在矫正局部后凸畸形及防止局部后凸畸形进一步进展方面效果更好。