Pietrangiolillo Zaira, Frassoldati Rossella, Leonelli Virginia, Freschi Rachele, Russomando Antonia, Lucaccioni Laura, Iughetti Lorenzo
Department of Pediatrics, University of Modena & Reggio Emilia, Modena, Italy.
Acta Biomed. 2012 Apr;83(1):44-50.
Snakebites in Italy are a rare source of severe medical condition, except in case of venomous snakes. The venom causes both local and/or systemic complication which may determine death in 6-60 hours, particularly in children and the elderly. In fact, the same amount of venom affects children more severely than adults because of the reduced total dilution volume in children. The only specific and conflicting therapy for venomous snakebite is to administer the appropriate anti-venom; the remaining therapy is symptomatic and supportive. We describe the case of a 22-month-old child who, despite appropriate symptomatic treatment, developed severe signs and an acute compartment syndrome of the right upper limb, a rare complication of venom snakebite. Administration of antivenom and fasciotomy were needed to resolve the acute episode permitting a positive outcome. On the basis of literature review and our experience we hypothesize an algorithm for the treatment of these patients.
在意大利,蛇咬伤是导致严重病症的罕见原因,除非是被毒蛇咬伤。蛇毒会引发局部和/或全身并发症,可能在6至60小时内导致死亡,儿童和老年人尤其如此。事实上,由于儿童的总稀释体积较小,相同剂量的毒液对儿童的影响比对成人更严重。针对毒蛇咬伤的唯一特效且存在争议的治疗方法是注射适当的抗蛇毒血清;其余治疗为对症和支持治疗。我们描述了一名22个月大儿童的病例,尽管进行了适当的对症治疗,但仍出现了严重症状和右上肢急性骨筋膜室综合征(毒蛇咬伤的一种罕见并发症)。需要注射抗蛇毒血清并进行筋膜切开术来解决急性发作,从而取得良好的治疗效果。基于文献综述和我们的经验,我们提出了一种针对这些患者的治疗方案。