Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Med Clin North Am. 2012 Sep;96(5):1001-19. doi: 10.1016/j.mcna.2012.07.008.
The prevalence of chemotherapy-related cardiac disease is increasing and management demands a multidisciplinary approach from cardiologists and oncologists. Pretreatment identification of predisposing risk factors and assessment of cardiac function before and at intervals during and after therapy with cardiotoxic agents are necessary. In clinical practice, surveillance is largely performed using transthoracic echocardiography or multi-gated radionuclide angiography. Imaging strategies that detect cardiac injury before overt left ventricular systolic dysfunction provide an opportunity for early intervention and improved cardiac outcomes.
化疗相关性心脏病的发病率正在上升，其治疗需要心脏病专家和肿瘤专家采取多学科的方法。在接受心脏毒性药物治疗之前、期间和之后，需要对易患风险因素进行预处理识别，并对心脏功能进行评估。在临床实践中，主要使用经胸超声心动图或多门控放射性核素血管造影术进行监测。在左心室收缩功能障碍出现之前检测心脏损伤的影像学策略为早期干预和改善心脏结局提供了机会。
