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骨髓水平出现类结节病样反应的不寻常表现,同时(18)F-FDG-PET/CT显示纵隔淋巴结肿大,类似霍奇金淋巴瘤早期复发。

Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on (18)F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma.

作者信息

Fallanca F, Picchio M, Crivellaro C, Mapelli P, Samanes Gajate A M, Sabattini E, Gianolli L, Messa C

机构信息

Nuclear Medicine Department, San Raffaele Scientific Institute, Milan, Italy.

出版信息

Rev Esp Med Nucl Imagen Mol. 2012 Jul-Aug;31(4):207-9. doi: 10.1016/j.remn.2012.03.002. Epub 2012 Apr 26.

DOI:10.1016/j.remn.2012.03.002
PMID:22980128
Abstract

(18)F-FDG-PET/CT is widely employed to evaluate lymphoma patients. False positive results are quite frequent, generally due to active phase of inflammation. We describe an unusual PET/CT presentation of a sarcoid-like reaction (SLR) in a patient monitored for Hodgkin Lymphoma characterized by an intense uptake in lymph nodes and multiple bone foci in a PET/CT study. The final diagnosis was obtained by biopsy. This study draws attention to the fact that multifocal bone marrow uptakes due to a sarcoideal reaction may be a possible cause of false positive results in (18)F-FDG-PET/CT studies in oncology patients.

摘要

(18)F-FDG-PET/CT被广泛用于评估淋巴瘤患者。假阳性结果相当常见,通常是由于炎症的活跃期。我们描述了一例在监测霍奇金淋巴瘤患者中出现的类肉瘤样反应(SLR)的不寻常PET/CT表现,其特征为在PET/CT检查中淋巴结和多个骨病灶有强烈摄取。最终诊断通过活检获得。本研究提请注意这样一个事实,即类肉瘤样反应引起的多灶性骨髓摄取可能是肿瘤患者(18)F-FDG-PET/CT研究中假阳性结果的一个可能原因。

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