Fallanca F, Picchio M, Crivellaro C, Mapelli P, Samanes Gajate A M, Sabattini E, Gianolli L, Messa C
Nuclear Medicine Department, San Raffaele Scientific Institute, Milan, Italy.
Rev Esp Med Nucl Imagen Mol. 2012 Jul-Aug;31(4):207-9. doi: 10.1016/j.remn.2012.03.002. Epub 2012 Apr 26.
(18)F-FDG-PET/CT is widely employed to evaluate lymphoma patients. False positive results are quite frequent, generally due to active phase of inflammation. We describe an unusual PET/CT presentation of a sarcoid-like reaction (SLR) in a patient monitored for Hodgkin Lymphoma characterized by an intense uptake in lymph nodes and multiple bone foci in a PET/CT study. The final diagnosis was obtained by biopsy. This study draws attention to the fact that multifocal bone marrow uptakes due to a sarcoideal reaction may be a possible cause of false positive results in (18)F-FDG-PET/CT studies in oncology patients.
(18)F-FDG-PET/CT被广泛用于评估淋巴瘤患者。假阳性结果相当常见,通常是由于炎症的活跃期。我们描述了一例在监测霍奇金淋巴瘤患者中出现的类肉瘤样反应(SLR)的不寻常PET/CT表现,其特征为在PET/CT检查中淋巴结和多个骨病灶有强烈摄取。最终诊断通过活检获得。本研究提请注意这样一个事实,即类肉瘤样反应引起的多灶性骨髓摄取可能是肿瘤患者(18)F-FDG-PET/CT研究中假阳性结果的一个可能原因。