美国东北部一座城市警察的抑郁症状与骨密度
Depressive symptoms and bone mineral density among police officers in a northeastern US City.
作者信息
Charles Luenda E, Fekedulegn Desta, Miller Diane B, Wactawski-Wende Jean, Violanti John M, Andrew Michael E, Burchfiel Cecil M
机构信息
National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia, USA.
出版信息
Glob J Health Sci. 2012 Apr 28;4(3):39-50. doi: 10.5539/gjhs.v4n3p39.
PURPOSE
The purpose of this study was to examine the association between depressive symptoms and bone mineral density (BMD).
METHODS
Depressive symptoms were measured using the Center for Epidemiologic Studies Depression (CES-D) scale. BMD of total hip, femoral neck, anterio-posterior (AP) spine, wrist, and total body were measured by DXA using standardized procedures. Mean levels of BMD across gender-specific tertiles of CES-D score were obtained using ANOVA and ANCOVA.
RESULTS
Participants included 97 police officers (41 women; 29-64 years). Depressive symptoms were not associated with BMD at any site among men. However among women, mean BMD values decreased across increasing (worsening) tertiles of CES-D for the AP spine (low CES-D=1.22 ± 0.04; medium CES-D=1.05±0.04; high CES-D=1.03±0.04 g/cm2; p=0.035) and for the whole body (low=1.26±0.03; medium=1.20±0.03; high=1.11±0.03 g/cm2; p=0.018) after adjustment.
CONCLUSIONS
Higher depressive symptoms were associated with lower BMD among female but not male officers.
目的
本研究旨在探讨抑郁症状与骨密度（BMD）之间的关联。
方法
使用流行病学研究中心抑郁量表（CES-D）来测量抑郁症状。采用标准化程序通过双能X线吸收法（DXA）测量全髋、股骨颈、腰椎前后位、腕部和全身的骨密度。使用方差分析（ANOVA）和协方差分析（ANCOVA）获得CES-D评分按性别分层的三分位数分组中的骨密度平均水平。
结果
研究对象包括97名警察（41名女性；年龄29 - 64岁）。男性中，抑郁症状与任何部位的骨密度均无关联。然而在女性中，调整后，腰椎前后位（低CES-D组 = 1.22 ± 0.04；中CES-D组 = 1.05 ± 0.04；高CES-D组 = 1.03 ± 0.04 g/cm²；p = 0.035）和全身（低 = 1.26 ± 0.03；中 = 1.20 ± 0.03；高 = 1.11 ± 0.03 g/cm²；p = 0.018）的骨密度均值随着CES-D评分三分位数的增加（抑郁症状加重）而降低。
结论
女性警察中，较高的抑郁症状与较低的骨密度相关，而男性警察中则无此关联。
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