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韩国女性骨质疏松症的患病率、知晓率和治疗率:第四次韩国国家健康和营养检查调查。

Prevalence, awareness, and treatment of osteoporosis among Korean women: The Fourth Korea National Health and Nutrition Examination Survey.

机构信息

Department of Family Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 28 Yunkeon-dong, Jongro-gu, Seoul, 110-744, Republic of Korea.

出版信息

Bone. 2012 May;50(5):1039-47. doi: 10.1016/j.bone.2012.02.007. Epub 2012 Feb 16.

Abstract

PURPOSE

This study aimed to assess the factors associated with the prevalence, awareness, and treatment of osteoporosis in a representative sample of Korean women.

METHODS

Data were obtained from dual energy X-ray absorptiometry measurement of the lumbar vertebrae and femoral neck, and from a standardized questionnaire in 2870 Korean women aged 50years and older who participated in the Fourth Korea National Health and Nutrition Examination Survey 2008-2009. Osteoporosis was defined by World Health Organization T-score criteria, and awareness and treatment were defined by self-report of an osteoporosis diagnosis and self-report of current anti-osteoporotic medication use, respectively. We assessed the relationship between multiple risk factors and prevalence, awareness, and treatment.

RESULTS

Osteoporosis was reported in 39.1% of Korean women. Among those with osteoporosis, only 37.5% were aware of their diagnosis and 23.5% received pharmacological treatment. Despite higher prevalence among respondents who were older, of lower body weight, calcium intake, physical activity, and education levels, the awareness and treatment rates of these groups were similar or lower than that of the low-risk controls in multivariate logistic regression models. Moreover, easily identifiable risk factors (e.g., history of fracture, falls, height loss, familial osteoporosis) were not associated with awareness and treatment. Participants who had undergone health screening in the previous 2years exhibited increased awareness and treatment rates independently of other demographic factors.

CONCLUSIONS

Osteoporosis was highly prevalent in this Korean study but was underdiagnosed and undertreated. Routine health screenings could be an effective strategy to increase osteoporosis awareness and treatment.

摘要

目的

本研究旨在评估与韩国女性骨质疏松症患病率、知晓率和治疗率相关的因素。

方法

数据来自于 2008-2009 年第四次韩国国家健康和营养检查调查中 2870 名 50 岁及以上的韩国女性腰椎和股骨颈双能 X 射线吸收法测量值,以及标准化问卷。骨质疏松症根据世界卫生组织 T 评分标准定义,知晓率和治疗率分别根据自我报告的骨质疏松症诊断和当前使用抗骨质疏松症药物的情况定义。我们评估了多种危险因素与患病率、知晓率和治疗率之间的关系。

结果

39.1%的韩国女性报告患有骨质疏松症。在患有骨质疏松症的患者中,仅有 37.5%知晓其诊断,23.5%接受了药物治疗。尽管年龄较大、体重较低、钙摄入量、身体活动和教育程度较高的患者骨质疏松症患病率较高,但在多变量逻辑回归模型中,这些组的知晓率和治疗率与低风险对照组相似或较低。此外,容易识别的危险因素(如骨折史、跌倒史、身高下降、家族性骨质疏松症)与知晓率和治疗率无关。在过去 2 年内接受过健康检查的参与者,不论其他人口统计学因素如何,其知晓率和治疗率均有所提高。

结论

在这项韩国研究中,骨质疏松症的患病率很高,但诊断不足且治疗不足。常规健康筛查可能是提高骨质疏松症知晓率和治疗率的有效策略。

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