Carles G, Helou J, Alassas N, Dallah F, Ibrahim N
Service de gynécologie-obstétrique, centre hospitalier Franck-Joly, avenue de Gaulle, 97320 Saint-Laurent-du-Maroni, Guyane française.
Gynecol Obstet Fertil. 2012 Oct;40(10):614-6. doi: 10.1016/j.gyobfe.2012.07.003. Epub 2012 Sep 13.
The authors report a heart failure and a collapse following concurrently administration of nicardipine and magnesium sulfate. These two drugs have potential negative inotropic effect and decrease systemic vascular resistance. Magnesium sulfate is the first-line treatment for the prevention of primary and recurrent eclamptic seizures. Combination with calcium channel blockers should be used cautiously.