Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
J Biosci Bioeng. 2013 Jan;115(1):96-9. doi: 10.1016/j.jbiosc.2012.08.012. Epub 2012 Sep 14.
Co-culture of human skeletal muscle myoblasts and fibroblasts was performed on a dendrimer-immobilized surface. Morphological changes by cytoskeletal variation were observed, compared with culture on a conventional tissue culture surface, and preferential growth of myoblasts can be achieved by inhibition of fibroblast growth.
人骨骼肌成肌细胞和成纤维细胞的共培养是在树枝状聚合物固定化表面上进行的。与传统的组织培养表面相比,观察到细胞骨架变化引起的形态变化,并通过抑制成纤维细胞生长来实现成肌细胞的优先生长。