• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

对于黑色素瘤患者行髂腹股沟淋巴结清扫术后早期活动并不会增加伤口并发症发生率。

Early mobilization after ilio-inguinal lymph node dissection for melanoma does not increase the wound complication rate.

机构信息

Division of Surgical Oncology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

出版信息

Eur J Surg Oncol. 2013 Feb;39(2):185-90. doi: 10.1016/j.ejso.2012.08.018. Epub 2012 Sep 13.

DOI:10.1016/j.ejso.2012.08.018
PMID:22981748
Abstract

AIM

Ilio-inguinal lymph node dissection for stage III melanoma is accompanied by a substantial amount of wound complications. Our treatment protocols changed in time in terms of postoperative bed rest prescriptions, being in chronological order Group A: 10 days with a Bohler Braun splint, Group B: 10 days without splint, and Group C: 5 days without splint. The aim of this study was to evaluate the effect of bed rest prescriptions on wound complications.

METHODS

For this study, we included all patients who underwent ilio-inguinal dissection for stage III melanoma in the period 1989-2011. Both univariate and multivariable analysis were performed to identify factors that were associated with occurrence of wound complications defined as wound infection, wound necrosis, and seroma.

RESULTS

Of the 204 patients analyzed, 99 suffered one or more wound complications: 51 wound infection, 29 wound necrosis, and 39 seroma. A wound complication occurred in 26 out of 64, 51 out of 89, and 22 out of 51 patients for Group A, B, and C, respectively. Univariate analysis showed age >55 (p = 0.001) and presence of comorbidity (p = 0.002) to be associated with higher incidence of wound complications. The 5 day bed rest protocol used in group C did not significantly increase the incidence of wound complications (ref = Group A: OR = 1.18; 95%CI = 0.52-2.68, p = 0.698).

CONCLUSION

Early mobilization did not significantly increase the overall wound complication rate after ilio-inguinal lymph node dissection for melanoma. Age >55 and comorbidity were risk factors in univariate analysis.

摘要

目的

III 期黑色素瘤的髂腹股沟淋巴结清扫术伴随着大量的伤口并发症。我们的治疗方案在术后卧床休息的规定方面及时改变,按时间顺序分为 A 组:使用 Bohler Braun 夹板 10 天,B 组:10 天不使用夹板,C 组:5 天不使用夹板。本研究旨在评估卧床休息规定对伤口并发症的影响。

方法

本研究纳入了 1989 年至 2011 年间所有接受髂腹股沟清扫术治疗 III 期黑色素瘤的患者。进行单因素和多因素分析,以确定与伤口并发症(定义为伤口感染、伤口坏死和血清肿)发生相关的因素。

结果

在分析的 204 名患者中,99 名患者发生了 1 种或多种伤口并发症:51 例伤口感染,29 例伤口坏死,39 例血清肿。A、B 和 C 组中,分别有 26 例、51 例和 51 例患者发生了伤口并发症。单因素分析显示,年龄>55 岁(p = 0.001)和合并症(p = 0.002)与伤口并发症发生率较高相关。C 组使用的 5 天卧床休息方案并未显著增加伤口并发症的发生率(参考 A 组:OR = 1.18;95%CI = 0.52-2.68,p = 0.698)。

结论

在黑色素瘤的髂腹股沟淋巴结清扫术后,早期活动并未显著增加总体伤口并发症发生率。年龄>55 岁和合并症是单因素分析中的危险因素。

相似文献

1
Early mobilization after ilio-inguinal lymph node dissection for melanoma does not increase the wound complication rate.对于黑色素瘤患者行髂腹股沟淋巴结清扫术后早期活动并不会增加伤口并发症发生率。
Eur J Surg Oncol. 2013 Feb;39(2):185-90. doi: 10.1016/j.ejso.2012.08.018. Epub 2012 Sep 13.
2
Therapeutic groin dissection for melanoma: risk factors for short term morbidity.黑色素瘤的治疗性腹股沟淋巴结清扫术:短期发病的危险因素
Eur J Surg Oncol. 2009 Aug;35(8):877-83. doi: 10.1016/j.ejso.2008.10.012. Epub 2008 Dec 2.
3
[Surgical technique and postoperative morbidity following radical inguinal/iliacal lymph node dissection--a prospective study in 67 patients with malignant melanoma metastatic to the groin].[根治性腹股沟/髂淋巴结清扫术后的手术技术及术后发病率——对67例腹股沟转移性恶性黑色素瘤患者的前瞻性研究]
Zentralbl Chir. 2009 Sep;134(5):437-42. doi: 10.1055/s-0029-1224608. Epub 2009 Sep 15.
4
Surgical wound complications after groin dissection in melanoma patients - a historical cohort study and risk factor analysis.黑色素瘤患者腹股沟清扫术后的手术伤口并发症——一项历史性队列研究及危险因素分析
Eur J Surg Oncol. 2014 Oct;40(10):1284-90. doi: 10.1016/j.ejso.2014.01.019. Epub 2014 Feb 20.
5
Morbidity After Inguinal Lymph Node Dissections: It Is Time for a Change.腹股沟淋巴结清扫术后的发病率:是时候做出改变了。
Ann Surg Oncol. 2017 Feb;24(2):330-339. doi: 10.1245/s10434-016-5461-3. Epub 2016 Aug 12.
6
The analysis of the outcomes and factors related to iliac-obturator involvement in cutaneous melanoma patients after lymph node dissection due to positive sentinel lymph node biopsy or clinically detected inguinal metastases.分析前哨淋巴结活检阳性或临床发现腹股沟转移的皮肤黑素瘤患者行淋巴结清扫术后与闭孔髂肌受累相关的结局和因素。
Eur J Surg Oncol. 2013 Mar;39(3):304-10. doi: 10.1016/j.ejso.2012.12.014. Epub 2013 Jan 5.
7
Lymph node dissection in patients with malignant melanoma is associated with high risk of morbidity.恶性黑色素瘤患者进行淋巴结清扫术会带来较高的发病风险。
Dan Med J. 2012 Jun;59(6):A4441.
8
Inguinal lymphadenectomy for stage III melanoma: a comparative study of two surgical approaches at the onset of lymphoedema.腹股沟淋巴结清扫术治疗 III 期黑色素瘤:淋巴水肿发病时两种手术方法的对比研究。
Eur J Surg Oncol. 2015 Feb;41(2):215-9. doi: 10.1016/j.ejso.2014.10.062. Epub 2014 Dec 9.
9
Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma.皮肤黑色素瘤患者腹股沟前哨淋巴结活检及根治性淋巴结清扫术后的发病率
Eur J Surg Oncol. 2006 Sep;32(7):785-9. doi: 10.1016/j.ejso.2006.05.003. Epub 2006 Jun 27.
10
Postoperative morbidity of lymph node excision for cutaneous melanoma-sentinel lymphonodectomy versus complete regional lymph node dissection.皮肤黑色素瘤淋巴结切除术后的发病率——前哨淋巴结切除术与区域淋巴结完全清扫术的比较
Melanoma Res. 2008 Feb;18(1):16-21. doi: 10.1097/CMR.0b013e3282f2017d.

引用本文的文献

1
Assessment and Reporting of Perioperative Adverse Events and Complications in Patients Undergoing Inguinal Lymphadenectomy for Melanoma, Vulvar Cancer, and Penile Cancer: A Systematic Review and Meta-analysis.黑色素瘤、外阴癌和阴茎癌患者腹股沟淋巴结清扫围手术期不良事件和并发症的评估与报告:一项系统评价和荟萃分析
World J Surg. 2023 Apr;47(4):962-974. doi: 10.1007/s00268-022-06882-6. Epub 2023 Jan 28.
2
Morbidity After Inguinal Lymph Node Dissections: It Is Time for a Change.腹股沟淋巴结清扫术后的发病率:是时候做出改变了。
Ann Surg Oncol. 2017 Feb;24(2):330-339. doi: 10.1245/s10434-016-5461-3. Epub 2016 Aug 12.
3
Dissections of regional lymph nodes for treatment of skin cancer: predicting annual caseloads that will optimise outcomes.
用于治疗皮肤癌的区域淋巴结解剖:预测能优化治疗效果的年度病例数。
Ann R Coll Surg Engl. 2015 Jan;97(1):52-5. doi: 10.1308/003588414X14055925059390.