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对于黑色素瘤患者行髂腹股沟淋巴结清扫术后早期活动并不会增加伤口并发症发生率。

Early mobilization after ilio-inguinal lymph node dissection for melanoma does not increase the wound complication rate.

机构信息

Division of Surgical Oncology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

出版信息

Eur J Surg Oncol. 2013 Feb;39(2):185-90. doi: 10.1016/j.ejso.2012.08.018. Epub 2012 Sep 13.

Abstract

AIM

Ilio-inguinal lymph node dissection for stage III melanoma is accompanied by a substantial amount of wound complications. Our treatment protocols changed in time in terms of postoperative bed rest prescriptions, being in chronological order Group A: 10 days with a Bohler Braun splint, Group B: 10 days without splint, and Group C: 5 days without splint. The aim of this study was to evaluate the effect of bed rest prescriptions on wound complications.

METHODS

For this study, we included all patients who underwent ilio-inguinal dissection for stage III melanoma in the period 1989-2011. Both univariate and multivariable analysis were performed to identify factors that were associated with occurrence of wound complications defined as wound infection, wound necrosis, and seroma.

RESULTS

Of the 204 patients analyzed, 99 suffered one or more wound complications: 51 wound infection, 29 wound necrosis, and 39 seroma. A wound complication occurred in 26 out of 64, 51 out of 89, and 22 out of 51 patients for Group A, B, and C, respectively. Univariate analysis showed age >55 (p = 0.001) and presence of comorbidity (p = 0.002) to be associated with higher incidence of wound complications. The 5 day bed rest protocol used in group C did not significantly increase the incidence of wound complications (ref = Group A: OR = 1.18; 95%CI = 0.52-2.68, p = 0.698).

CONCLUSION

Early mobilization did not significantly increase the overall wound complication rate after ilio-inguinal lymph node dissection for melanoma. Age >55 and comorbidity were risk factors in univariate analysis.

摘要

目的

III 期黑色素瘤的髂腹股沟淋巴结清扫术伴随着大量的伤口并发症。我们的治疗方案在术后卧床休息的规定方面及时改变,按时间顺序分为 A 组:使用 Bohler Braun 夹板 10 天,B 组:10 天不使用夹板,C 组:5 天不使用夹板。本研究旨在评估卧床休息规定对伤口并发症的影响。

方法

本研究纳入了 1989 年至 2011 年间所有接受髂腹股沟清扫术治疗 III 期黑色素瘤的患者。进行单因素和多因素分析,以确定与伤口并发症(定义为伤口感染、伤口坏死和血清肿)发生相关的因素。

结果

在分析的 204 名患者中,99 名患者发生了 1 种或多种伤口并发症:51 例伤口感染,29 例伤口坏死,39 例血清肿。A、B 和 C 组中,分别有 26 例、51 例和 51 例患者发生了伤口并发症。单因素分析显示,年龄>55 岁(p = 0.001)和合并症(p = 0.002)与伤口并发症发生率较高相关。C 组使用的 5 天卧床休息方案并未显著增加伤口并发症的发生率(参考 A 组:OR = 1.18;95%CI = 0.52-2.68,p = 0.698)。

结论

在黑色素瘤的髂腹股沟淋巴结清扫术后,早期活动并未显著增加总体伤口并发症发生率。年龄>55 岁和合并症是单因素分析中的危险因素。

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