Lucarini N, Finocchi G, Gloria-Bottini F, Macioce M, Borgiani P, Amante A, Bottini E
Chair of Human Development, 2nd University of Rome School of Medicine, Italy.
Experientia. 1990 Jan 15;46(1):90-1. doi: 10.1007/BF01955426.
Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association.