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将带倒钩的可回收自扩张金属支架置入患有梗阻性前列腺癌的患者体内。

Placement of retrievable self-expandable metallic stents with barbs into patients with obstructive prostate cancer.

机构信息

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, 388-1, Poongnap 2-dong, Songpa-gu, Seoul 138-736, Republic of Korea.

出版信息

Eur Radiol. 2013 Mar;23(3):780-5. doi: 10.1007/s00330-012-2650-8. Epub 2012 Sep 16.

Abstract

OBJECTIVES

To evaluate the technical feasibility and clinical effectiveness of retrievable self-expandable metallic stents with barbs in patients with obstructive prostate cancer.

METHODS

Retrievable self-expandable metallic stents with eight barbs each were inserted into eight consecutive patients with obstructive prostate cancer. Patient ages ranged from 55 to 76 years (mean, 69 years). All eight patients had previously received hormone therapy, and three had undergone palliative transurethral prostatectomy. Stents were removed using a 21-F stent removal set if they caused complications.

RESULTS

Stent placement was technically successful and well tolerated in all patients. One had severe incontinence, which improved spontaneously, and two had gross haematuria, which disappeared spontaneously within 4 days. Peak urine flow rates and post-void residual urine volumes 1 month after stent placement were 5.6-10.2 ml/s (mean, 8.3 ml/s), and 5-45 ml (mean, 27 ml), respectively. During a mean follow-up of 192 days (range, 39-632 days), one patient required stent removal after 232 days because of stone formation within the stent. No further intervention was required because the mass improved after stent removal.

CONCLUSIONS

These preliminary results suggest that retrievable stents with eight barbs are both feasible to place and effective in patients with obstructive prostate cancer.

摘要

目的

评估带倒刺可回收自膨式金属支架治疗前列腺癌梗阻的技术可行性和临床疗效。

方法

连续 8 例前列腺癌梗阻患者置入带 8 个倒刺的可回收自膨式金属支架。患者年龄 55-76 岁,平均 69 岁。所有患者均接受过激素治疗,3 例行姑息性经尿道前列腺切除术。若发生并发症则使用 21-F 支架取出器取出支架。

结果

所有患者支架置入技术均成功,且患者均能耐受。1 例发生严重尿失禁,自行缓解;2 例发生肉眼血尿,4 天内自行消失。支架置入 1 个月后最大尿流率和残余尿量分别为 5.6-10.2ml/s(平均 8.3ml/s)和 5-45ml(平均 27ml)。平均随访 192 天(39-632 天),1 例患者在 232 天时因支架内结石形成而取出支架。支架取出后,患者病情改善,无需进一步干预。

结论

这些初步结果表明,带 8 个倒刺的可回收支架在治疗前列腺癌梗阻患者中是可行且有效的。

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