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依维莫司致药物洗脱支架置入术后肺炎:1 例报告。

Everolimus-induced pneumonitis after drug-eluting stent implantation: a case report.

机构信息

Department of Respiratory Medicine, Toho University School of Medicine, Tokyo, Japan.

出版信息

Cardiovasc Intervent Radiol. 2013 Aug;36(4):1151-4. doi: 10.1007/s00270-012-0477-y. Epub 2012 Sep 15.

DOI:10.1007/s00270-012-0477-y
PMID:22983698
Abstract

Despite the wide use of everolimus as an antineoplastic coating agent for coronary stents to reduce the rate of restenosis, little is known about the health hazards of everolimus-eluting stents (EES). We describe a case of pneumonitis that developed 2 months after EES implantation for angina. Lung pathology demonstrated an organizing pneumonia pattern that responded to corticosteroid therapy. Although the efficacy of EES for ischemic heart disease is well established, EES carries a risk of pneumonitis.

摘要

尽管依维莫司被广泛用作冠状动脉支架的抗肿瘤涂层剂,以降低再狭窄率,但对于依维莫司洗脱支架(EES)的健康危害知之甚少。我们描述了一例因心绞痛植入 EES 后 2 个月发生的肺炎病例。肺部病理学表现为机化性肺炎模式,对皮质类固醇治疗有反应。尽管 EES 治疗缺血性心脏病的疗效已得到充分证实,但 EES 存在发生肺炎的风险。

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