Taylor J L
University of Alabama, Birmingham.
Geriatrics. 1990 Feb;45(2):35-8, 43.
Given the evidence that treating hypertension reduces the morbidity and mortality associated with it, and given the demonstrated effectiveness of the antihypertensive agents available, the number of inadequately controlled patients is disturbing. Failed or inadequate antihypertensive therapy may be due to aging-related pharmacokinetic and pharmacodynamic changes, drug interactions, poor patient compliance, or poor communication between physician and patient. By understanding the reasons for therapeutic failure in hypertension, the primary care physician is in a position to remedy the problem. It is the uncommon patient whose blood pressure can not be controlled if the doctor is giving proper advice which the patient then follows.
鉴于治疗高血压可降低与之相关的发病率和死亡率,且现有抗高血压药物已证实有效,但血压控制不佳的患者数量却令人担忧。抗高血压治疗失败或效果不佳可能是由于与年龄相关的药代动力学和药效学变化、药物相互作用、患者依从性差,或医生与患者之间沟通不良。通过了解高血压治疗失败的原因,初级保健医生能够解决这一问题。如果医生给出恰当建议且患者听从,那么血压无法得到控制的患者是罕见的。