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大疱性 Darier 病酷似 Hailey-Hailey 病。

Bullous Darier's disease mimicking Hailey-Hailey disease.

机构信息

Department of Dermatology, Charles Nicolle Hospital, Boulevard 9 Avril, 1006 Tunis, Tunisia.

出版信息

Dermatol Ther (Heidelb). 2011 Dec;1(2):31-5. doi: 10.1007/s13555-011-0007-x. Epub 2011 Oct 25.

Abstract

BACKGROUND

The bullous variant of Darier's disease (DD) is a rare type characterized by histological and clinical overlap with Hailey-Hailey disease (HDD).

CASE REPORTS

The following case report describes two cases of familial DD; a 51-year-old woman who presented with erythematous plaques, covered by small blisters in axillary and inguinal areas, and the first patient's daughter, who presented with keratotic papules localized on the axillary and inframammary folds.

CONCLUSION

These two cases are original by the predominant flexural distribution, and by a bullous form in the first case, clinically and histologically mimicking HHD.

摘要

背景

大疱性 Darier 病(DD)是一种罕见的疾病类型,其组织学和临床表现与 Hailey-Hailey 病(HDD)重叠。

病例报告

以下病例报告描述了两例家族性 DD 病例;一名 51 岁女性,表现为红斑,腋窝和腹股沟区域覆盖小水疱,以及第一例患者的女儿,表现为腋窝和乳房下褶皱处的角化丘疹。

结论

这两例病例的特点是主要分布于弯曲部位,且第一例表现为大疱性,在临床上和组织学上均类似于 HHD。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e1/3721533/3fcf19f706c0/13555_2011_7_Fig1_HTML.jpg

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