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[从高加索地区自然疫源地分离出的鼠疫耶尔森氏菌田鼠菌株的系统地理学研究]

[The phylogeography of the Yersinia pestis vole strains isolated from the natural foci of caucasian region].

作者信息

Platonov M E, Evseeva V V, Svetoch T E, Efremenko D V, Kuznetsova I V, Dentovskaia S V, Kulichenko A N, Anisimov A P

出版信息

Mol Gen Mikrobiol Virusol. 2012(3):18-21.

Abstract

57 Y pestis bv. caucasica strains were assayed using molecular typing. The results of these assays indicated the presence within this biovar of the three separate clonal clusters and necessity of detachment of the Leninakan mountain mesofocus (subfocus) from the structure of Transcaucasian-highland focus into self-supporting one, as well as inclusion of a part of the Pre-Araks low-mountain natural plague focus in the capacity of the subfocus along with Pre-Sevan mountain and Zanzegur-Karabakh mountain subfoci into the structure of Transcaucasian-highland focus. It was shown that the strains circulating in the East-Caucasian highland plague focus were the most ancient branch of bv. caucasica or even of the entire Y pestis phylogenetic tree.

摘要

使用分子分型方法对57株鼠疫杆菌高加索生物变种菌株进行了分析。这些分析结果表明,在该生物变种中存在三个独立的克隆簇,并且有必要将列宁纳坎山区中型疫源地(子疫源地)从外高加索高地疫源地结构中分离出来,使其成为一个独立的疫源地,同时将阿拉克斯河前低山自然鼠疫疫源地的一部分作为子疫源地,连同塞凡湖前山区和赞格祖尔-卡拉巴赫山区子疫源地一起纳入外高加索高地疫源地结构。结果表明,在东高加索高地鼠疫疫源地传播的菌株是高加索生物变种甚至是整个鼠疫杆菌系统发育树中最古老的分支。

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