Luo Xiaoyan, Xu Liangzhi
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1325-7.
To study the characteristics of the metabolic syndrome (MS) in patients with polycystic ovary syndrome (PCOS).
Oral glucose tolerance test (OGTT) was performed in 336 patients with PCOS, and the serum levels triglycerides (TG), total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and testosterone were measured.
The total incidence of MS was 18.8% in these 336 patients with PCOS. The incidence of MS increased with percent body fat (%BF) and lipid accumulation product (LAP) in patients with PCOS. The patients at child-bearing age appeared to have a higher incidence of MS than those in puberty. The muscle distribution coefficient, age, body mass index, and the metabolic parameters were all higher in patients with MS than in those without MS. The bilateral lower limb muscle strength were lower in patients with MS than in those without, but the level of testosterone showed no significant difference between them.
The risk of MS increases with BF%, age and LAP in patients with PCOS.
研究多囊卵巢综合征（PCOS）患者代谢综合征（MS）的特征。
对336例PCOS患者进行口服葡萄糖耐量试验（OGTT），并检测血清甘油三酯（TG）、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和睾酮水平。
这336例PCOS患者中MS的总发生率为18.8%。PCOS患者中MS的发生率随体脂百分比（%BF）和脂质蓄积产物（LAP）升高而增加。育龄期患者的MS发生率似乎高于青春期患者。MS患者的肌肉分布系数、年龄、体重指数和代谢参数均高于非MS患者。MS患者双侧下肢肌肉力量低于非MS患者，但两者睾酮水平无显著差异。
PCOS患者发生MS的风险随BF%、年龄和LAP升高而增加。
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