Samulski T V, Fessenden P, Lee E R, Kapp D S, Tanabe E, McEuen A
Department of Radiation Oncology, Stanford University School of Medicine, CA.
Int J Radiat Oncol Biol Phys. 1990 Jan;18(1):233-42. doi: 10.1016/0360-3016(90)90288-u.
Spiral microstrip microwave (MW) antennas have been developed and adapted for use as clinical hyperthermia applicators. The design has been configured in a variety of forms including single fixed antenna applicators, multi-element arrays, and mechanically scanned single or paired antennas. The latter three configurations have been used to allow an expansion of the effective heating area. Specific absorption rate (SAR) distributions measured in phantom have been used to estimate the depth and volume of effective heating. The estimates are made using the bioheat equation assuming uniformly perfused tissue. In excess of 500 treatments of patients with advanced or recurrent localized superficial tumors have been performed using this applicator technology. Data from clinical treatments have been analyzed to quantify the heating performance and verify the suitability of these applicators for clinical use. Good microwave coupling efficiency together with the compact applicator size have proved to be valuable clinical assets.
螺旋微带微波（MW）天线已被开发并适用于临床热疗应用。其设计有多种形式，包括单固定天线应用器、多单元阵列以及机械扫描的单天线或双天线。后三种配置用于扩大有效加热区域。在体模中测量的比吸收率（SAR）分布已用于估计有效加热的深度和体积。这些估计是使用生物热方程并假设组织灌注均匀得出的。使用这种应用器技术已对500多名晚期或复发性局部浅表肿瘤患者进行了治疗。已对临床治疗数据进行分析，以量化加热性能并验证这些应用器在临床使用中的适用性。良好的微波耦合效率以及紧凑的应用器尺寸已被证明是宝贵的临床优势。
