Jones Kate, Cocker John, Piney Mark
Health & Safety Laboratory, Harpur Hill, Buxton, SK17 9JN, UK.
Ann Occup Hyg. 2013 Mar;57(2):200-9. doi: 10.1093/annhyg/mes056. Epub 2012 Sep 17.
The purpose of this work was to assess the changes in control of exposure to hexamethylene diisocyanate based paints used in vehicle spraying after a Health & Safety Executive (HSE) national project.
Paint sprayers and managers from motor vehicle repair (MVR) bodyshops across the UK, were invited to one of 32 Safety and Health Awareness Days (SHADs) to increase their understanding of the hazards, and practical ways of controlling of exposure to isocyanate based paints. Exposure measurement based on biological monitoring was offered, free of charge, to each of the roughly 4000 participants and used to assess the effectiveness of controls and methods of working. Results are compared with pre and post SHAD measurements.
Urine samples were received from 995 paint sprayers. Hexamethylene diamine (HDA) levels in urine, indicative of exposure to hexamethylene diisocyanate (HDI), were significantly lower (Mann-Whitney, p<0.0001) than had been seen in a wider population from previous HSE inspections and routine sampling. Where a sprayer's urinary HDA was above the quantification limit they were asked to send another sample after reviewing and improving exposure control measures. The results from these repeat samples were significantly lower than the original results. There was no difference in the exposures of sprayers using air-fed half-mask face-pieces compared with visor type air-fed breathing apparatus, or between spray booths and rooms.
The analysis of HDA in urine is a useful technique for assessing exposure to isocyanates in paint sprayers. The simplicity of this approach has allowed wide-scale use of biological monitoring in an industry dominated by small and micro businesses. Biological monitoring of exposure has enabled individual companies, and sprayers, to check that their control measures are working. This study showed overall lower levels of HDA in paint sprayers following SHADs. These lower levels have been maintained across a wider population of UK paint sprayers over the succeeding years. Whilst there may be many reasons for the reduction in exposure, the weight of evidence suggests that the key messages about exposure control measures, delivered through the SHADs and other means, were influential.
本研究旨在评估健康与安全执行局(HSE)的一个全国性项目之后,车辆喷漆中使用的基于六亚甲基二异氰酸酯的涂料的接触控制情况变化。
邀请全英国机动车维修(MVR)车身修理厂的喷漆工和管理人员参加32场安全与健康宣传日(SHADs)活动中的一场,以增进他们对危害的理解,以及控制异氰酸酯基涂料接触的实用方法。为大约4000名参与者每人免费提供基于生物监测的接触测量,并用于评估控制措施和工作方法的有效性。将结果与SHADs活动前后的测量结果进行比较。
收到了995名喷漆工的尿液样本。尿液中六亚甲基二胺(HDA)水平表明接触了六亚甲基二异氰酸酯(HDI),与HSE之前检查和常规采样的更广泛人群相比,该水平显著降低(曼-惠特尼检验,p<0.0001)。当喷漆工的尿HDA高于定量限时,要求他们在审查和改进接触控制措施后再送一份样本。这些重复样本的结果显著低于原始结果。使用供气式半面罩的喷漆工与使用面罩式供气呼吸器的喷漆工之间,以及喷漆房和喷漆室之间的接触情况没有差异。
尿液中HDA的分析是评估喷漆工异氰酸酯接触情况的有用技术。这种方法的简单性使得生物监测能够在以小微企业为主的行业中广泛应用。接触的生物监测使各个公司和喷漆工能够检查他们的控制措施是否有效。本研究表明,SHADs活动后喷漆工的HDA总体水平较低。在随后几年中,英国更广泛的喷漆工群体中一直保持着这些较低水平。虽然接触减少可能有多种原因,但证据表明,通过SHADs活动和其他方式传达的关于接触控制措施的关键信息具有影响力。