Konagurthu Arun S, Lesk Arthur M
Clayton School of Information Technology, Monash University, Clayton, VIC, Australia.
Methods Mol Biol. 2013;932:51-9. doi: 10.1007/978-1-62703-065-6_4.
We have developed a concise tableau representation of protein folding patterns, based on the order and contact patterns of elements of secondary structure: helices and strands of sheet. The tableaux provide a database, derived from the protein data bank, minable for studies on the general principles of protein architecture, including investigation of the relationship between local supersecondary structure of proteins and the complete folding topology. This chapter outlines the tableaux representation of protein folding patterns and methods to use them to identify structural and substructural similarities.
我们基于二级结构元件（螺旋和片层的链）的顺序和接触模式，开发了一种简洁的蛋白质折叠模式表格表示法。这些表格提供了一个源自蛋白质数据库的数据库，可用于研究蛋白质结构的一般原理，包括研究蛋白质局部超二级结构与完整折叠拓扑之间的关系。本章概述了蛋白质折叠模式的表格表示法以及使用它们来识别结构和亚结构相似性的方法。
