Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore.
Chemistry. 2012 Oct 29;18(44):13979-83. doi: 10.1002/chem.201202711. Epub 2012 Sep 17.
On and off: ester hydrolysis catalyzed by a Zn(II) -coordinated β-cyclodextrin dimer can be switched on and off using light in the presence of gold nanoparticles with azobenzene units attached to their surfaces. Under visible light, the azobenzene units are trans and bind tightly to the dimer, thus leading to reduced catalysis. Under UV light, the azobenzene units are cis and bind loosely to the dimer, thus allowing substrates to bind and hydrolysis to occur.
在金纳米粒子存在的情况下，用光可以打开和关闭由 Zn(II) 配位的β-环糊精二聚体催化的酯水解反应，这些金纳米粒子的表面连接有偶氮苯单元。在可见光下，偶氮苯单元处于反式构型，与二聚体紧密结合，从而导致催化作用降低。在紫外光下，偶氮苯单元处于顺式构型，与二聚体松散结合，从而允许底物结合并发生水解反应。
