Zerem Enver, Imamović Goran, Latić Ferid, Mavija Zoran
Department of Gastroenterology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.
J Clin Ultrasound. 2013 May;41(4):203-9. doi: 10.1002/jcu.21995. Epub 2012 Sep 18.
To evaluate the prognostic value of acute fluid collections (AFC) diagnosed by conventional transabdominal ultrasound in the early assessment of severity acute pancreatitis (AP).
We studied 128 consecutive patients with AP between March 2006 and March 2011. The predictor was the number of AFC. Outcome measure was the occurrence of complications. Abdominal sonogram, contrast-enhanced CT, and pancreatitis-specific clinical and laboratory findings were performed.
AFC were associated with complications (p < 0.0001), Balthazar grade (p = 0.004), Ranson score (p < 0.0001), and the majority of clinical, radiologic, and biochemical parameters for predicting complications of AP (p < 0.05). Univariate logistic regression also revealed significant association between the number of AFC and the occurrence of complications (OR 4.4; 95% CI 2.5-7.6). After the adjustment for covariates, AFC remained prognostic for complications and a cutoff point of >1 AFC was prognostic of their occurrence with 88% sensitivity and 82% specificity.
AFC are related to the clinical course of AP and can predict its severity
评估经传统经腹超声诊断的急性液体积聚（AFC）在急性胰腺炎（AP）严重程度早期评估中的预后价值。
我们研究了2006年3月至2011年3月期间连续收治的128例AP患者。预测指标为AFC的数量。观察指标为并发症的发生情况。进行了腹部超声检查、增强CT检查以及胰腺炎特异性的临床和实验室检查。
AFC与并发症（p < 0.0001）、巴尔萨泽分级（p = 0.004）、兰森评分（p < 0.0001）以及大多数预测AP并发症的临床、放射学和生化参数相关（p < 0.05）。单因素逻辑回归分析也显示AFC数量与并发症的发生之间存在显著关联（比值比4.4；95%置信区间2.5 - 7.6）。在对协变量进行调整后，AFC对并发症仍具有预后价值，AFC数量>1个的截断点对并发症发生的预测敏感性为88%，特异性为82%。
AFC与AP的临床病程相关，可预测其严重程度
